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prof. dr. J.M. (Jaap) van Laar

prof. dr. J.M. (Jaap) van Laar

Full Professor
prof. dr. J.M. (Jaap) van Laar
  • Rheumatology & Clinical Immunology

Biography

Biography

Jacob M. van Laar is Professor at the Department of Rheumatology and Clinical Immunology at UMC Utrecht, the Netherlands. After obtaining his MD and PhD degrees at Leiden University, he specialised in Internal Medicine and Rheumatology in Leiden University Medical Center and worked at the Department of Rheumatology as clinical academic in various roles from 1997-2007, interrupted by a postdoctoral research fellowship at the National Institute of Arthritis and Musculoskeletal and Skin Diseases in Bethesda, USA. From 2007 until 2013 he held a Chair in Clinical Rheumatology at Newcastle University, and post as honorary consultant rheumatologist at The James Cook University Hospital, Middlesbrough, UK. He has been working as Professor of Rheumatology at UMC Utrecht since 1 November 2013. His main research interests involve clinical and pathogenetic aspects of systemic sclerosis and rheumatoid arthritis, aimed at improving the outcome of patients with rheumatic diseases by innovative clinical-translational research.

Side Activities

Member EULAR Scientific Programme Committee 

Chair Society for Rheumatology Research Utrecht (SRU)

Founding Member Stichting ARCH

Member Scientific Advisory Board Edith Busch Stiftung

Member of EUSTAR (EULAR Scleroderma Trials and Research)

Ad hoc expert advice Central Board of Appeal, consultancies pharmaceutical companies (www.transparantieregister.nl), postgraduate teaching (including Artrose Instituut Nederland), patient consultations (Reumazorg Zuid-West Nederland).

 

 

Fellowship and Awards

Marie Parijs award for pioneering work in the field of clinical stem cell research in rheumatic autoimmune diseases (2002, Leiden University Medical Center)

ZonMW Clinical Fellow (2007)

Fellow of the Royal College of Physicians Edinburgh (2009)

NVLE Award (2015) 

Research Output (296)

Current Smoking Negatively Affects the Response to Methotrexate in Rheumatoid Arthritis in a Dose-responsive Way, Independently of Concomitant Prednisone Use

Safy-Khan Mary, de Hair Maria J H, Welsing Paco M J, van Laar Jacob M, Jacobs Johannes W G, 1 okt 2021, In: Journal of Rheumatology. 48 , p. 1504-1507 4 p.

Microarray testing in patients with systemic lupus erythematosus identifies a high prevalence of CpG DNA-binding antibodies

Brunekreef Tammo, Limper Maarten, Melchers Rowena, Mathsson-Alm Linda, Dias Jorge, Hoefer Imo, Haitjema Saskia, van Laar Jacob M, Otten Henny okt 2021, In: Lupus science & medicine. 8

Clinical Practice Audit on the Management of Antineutrophil Cytoplasmic Antibody-Associated Vasculitis in the Netherlands

Dirikgil Ebru, Jonker Jacqueline T, Tas Sander W, Verburgh Cornelis A, Soonawala Darius, Hak A Elisabeth, Remmelts Hilde H F, IJpelaar Daphne, Laverman Gozewijn D, Rutgers Abraham, van Laar Jacob M, Moen Hein J Bernelot, Verhoeven Peter M J, Rabelink Ton J, Bos Willem Jan W, Teng Y K Onno, okt 2021, In: Kidney International Reports. 6 , p. 2671-2678 8 p.

Predictors for progressive fibrosis in patients with connective tissue disease associated interstitial lung diseases

Chiu Yu Hsiang, Spierings Julia, de Jong Pim A., Hoesein Firdaus Mohamed, Grutters Jan C., van Laar Jacob M., Voortman Mareye 18 aug 2021, In: Respiratory Medicine. 187 8 p.

Identification and prediction of difficult-to-treat rheumatoid arthritis patients in structured and unstructured routine care data:results from a hackathon

Messelink Marianne A., Roodenrijs Nadia M.T., van Es Bram, Hulsbergen-Veelken Cornelia A.R., Jong Sebastiaan, Overmars L. Malin, Reteig Leon C., Tan Sander C., Tauber Tjebbe, van Laar Jacob M., Welsing Paco M.J., Haitjema Saskia 8 jul 2021, In: Arthritis Research and Therapy. 23

AZD9567 VERSUS PREDNISOLONE IN PATIENTS WITH ACTIVE RHEUMATOID ARTHRITIS: A PHASE 2A, RANDOMISED, DOUBLE-BLIND, PARALLEL-GROUP EFFICACY AND SAFETY STUDY

Van Laar J. M., Lei A., Safy-Khan M., Almquist J., Astbury C., Belvisi M., Platt A., Prothon S., Samuelsson S., Svanberg P., Keen C. jun 2021, In: Annals of the Rheumatic Diseases. 80 , p. 253-254

PERSONALISED TREATMENT GOALS IN PATIENTS WITH IMMUNE MEDIATED INFLAMMATORY DISEASE

Fadaei S., Van Os-Medendorp H., Sloeserwij A., Sigurdsson V., Van Laar J. M., Spierings J. jun 2021, In: Annals of the Rheumatic Diseases. 80 , p. 1465-1466

BIOMARKERS FOR CONNECTIVE TISSUE DISEASE-ASSOCIATED INTERSTITIAL LUNG DISEASE: A PILOT STUDY

Chiu Y. H., Voortman M., Delemarre E. M., Nierkens S., De Jong P., Hoesein F. Mohamed, Van Laar J. M., Spierings J. jun 2021, In: Annals of the Rheumatic Diseases. 80 , p. 1430-1431

PREDICTIVE FACTORS FOR PULMONARY PROGRESSION IN PATIENTS WITH CONNECTIVE TISSUE DISEASE AND INTERSTITIAL LUNG DISEASE

Chiu Y. H., Spierings J., De Jong P., Hoesein F. Mohamed, Van Laar J. M., Voortman M. jun 2021, In: Annals of the Rheumatic Diseases. 80 , p. 993-993

A randomised, open-label trial to assess the optimal treatment strategy in early diffuse cutaneous systemic sclerosis:the UPSIDE study protocol

Spierings Julia, van Rhenen Anna, Welsing Paco Mw, Marijnissen Anne Ca, De Langhe Ellen, Del Papa Nicoletta, Dierickx Daan, Gheorghe Karina R, Henes Joerg, Hesselstrand Roger, Kerre Tessa, Ljungman Per, van de Loosdrecht Arjan A, Marijt Erik Waf, Mayer Miro, Schmalzing Marc, Schroers Roland, Smith Vanessa, Voll Reinhard E, Vonk Madelon C, Voskuyl Alexandre E, de Vries-Bouwstra Jeska K, Walker Ulrich A, Wuttge Dirk M, van Laar Jacob M 18 mrt 2021, In: BMJ Open. 11

All research output

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