prof. dr. F.P.J.G. (Floris) Lafeber
prof. dr. F.P.J.G. (Floris) Lafeber

- Rheumatology & Clinical Immunology
Research Programs
Biography
Biography
Floris Lafeber (1961) is professor of ‘Experimental Rheumatology’ at the UMC Utrecht. He studied Biology at the University of Nijmegen (NL; graduated Nov 1984) and did his PhD at this University in collaboration with the Univerity of Leiden (NL), with a visit of three months at the department of Physiology, Univ. of Ottawa (Canada) (graduated April 1988). He is scientifically active in the field of ‘Regenerative Medicine’ and ‘Immunology’.
Currently, his main research interest is in 1) Implementation of joint distraction in the treatment of knee osteoarthritis; 2) The potential of IL4-10 synerkine in control of cartilage damage, inflammation, and pain in osteoarthritis (and haemophilic arthropathy); 3) The prediction of progression and response to treatment in osteoarthritis, rheumatoid arthritis, and haemophilic arthropathy.
Floris Lafeber is (co-)author of over 300 peer-reviewed papers (H-index 48), of which more than half in the top 10% of the field. He co-supervised 30 PhD students with several additionally scheduled. He has several patent (provisional) in the fields described above, and gained over his career for more than 15 million Euros research funding from the Dutch Arthritis Association, government, and industry. At present he is manager of research and head of research laboratory of the department of Rheumatology & Clinical Immunology, UMCU (3 days/week)
Side Activities
Manager Research of the Division of Internal Medicine & Dermatology (2018 - present) 1 day/week
Member of the steering committee of APPROACH within IMI (2015-2021)
Member of: OsteoArthritis Research Society International (OARSI); Orthopaedic Research Society (ORS); and International Cartilage Repair Society (ICRS) (present)
Member of the Advisory Board Biobanking (2019-present)
Consultant: SynerkinePharma BV
Reviewer for several international journals and funding agencies
Research Output (441)
Roemer Frank W, Jansen Mylène, Marijnissen Anne C A, Guermazi Ali, Heiss Rafael, Maschek Susanne, Lalande Agnes, Blanco Francisco J, Berenbaum Francis, van de Stadt Lotte A, Kloppenburg Margreet, Haugen Ida K, Ladel Christoph H, Bacardit Jaume, Wisser Anna, Eckstein Felix, Lafeber Floris P J G, Weinans Harrie H, Wirth Wolfgang 17 Nov 2022, In: BMC Musculoskeletal Disorders. 23
Verhoeven Maxime M.A., Westgeest Anton A.A., Tekstra Janneke, van Laar Jacob M., Lafeber Floris P.J.G., Welsing Paco M.J., Jacobs Johannes W.G. 1 Nov 2022, In: Clinical and Experimental Rheumatology. 40 , p. 2018-2022 5 p.
Kleinrensink Nienke J., Perton Frank T., Pouw Juliëtte N., Vincken Nanette L.A., Hartgring Sarita A.Y., Jansen Mylène P., Arbabi Saeed, Foppen Wouter, de Jong Pim A., Tekstra Janneke, Leijten Emmerik F.A., Spierings Julia, Lafeber Floris P.J.G., Welsing Paco M.J., Heijstek Marloes W., 10 Oct 2022, In: BMJ Open. 12 , p. 1-11
Mastbergen S C, Ooms A, Turmezei T D, MacKay J W, Van Heerwaarden R J, Spruijt S., Lafeber F P J G, Jansen M P Jul 2022, In: Osteoarthritis and Cartilage. 30 , p. 965-972 8 p.
van Bergen E. D.P., Monnikhof M., Lafeber F. P.J.G., Schutgens R. E.G., Mastbergen S. C., van Vulpen L. F.D. 24 Jun 2022, In: Blood Reviews. 56
Messelink Marianne A., van der Leeuw Matthijs S., den Broeder Alfons A., Tekstra Janneke, van der Goes Marlies C., Heijstek Marloes W., Lafeber Floris, Welsing Paco M.J. 16 Jun 2022, In: Trials. 23
Hinrichs Anneline C., Blokland Sofie L.M., Kruize Aike A., Lafeber Floris P.J., Leavis Helen L., van Roon Joel A.G. 1 Jun 2022, In: Frontiers in Immunology. 13 , p. 1-10
van Helvoort Eefje M, Jansen Mylène P, Marijnissen Anne C A, Kloppenburg Margreet, Blanco Francisco J, Haugen Ida K, Berenbaum Francis, Bay-Jensen Anne-Christine C, Ladel Christoph, Lalande Agnes, Larkin Jonathan, Loughlin John, Mobasheri Ali, Weinans Harrie H, Widera Pawel, Bacardit Jaume, Welsing Paco M J, Lafeber Floris P J G 16 May 2022, In: Rheumatology (Oxford, England). 62 , p. 147-157 11 p.
van der Leeuw Matthijs S., Messelink Marianne A., Tekstra Janneke, Medina Ojay, van Laar Jaap M., Haitjema Saskia, Lafeber Floris, Veris-van Dieren Josien J., van der Goes Marlies C., den Broeder Alfons A., Welsing Paco M.J. 23 Mar 2022, In: Arthritis research & therapy. 24 , p. 1-11
van Helvoort Eefje M, Hodgins D, Mastbergen Simon C, Marijnissen Anne C A, Kloppenburg M, Blanco Fransisco J, Haugen Ida K, Berenbaum F, Lafeber Floris P J G, Welsing Paco M J Mar 2022, In: PLoS ONE. 17 , p. 1-13