dr. M.L. Houben

dr. M.L. Houben

Assistant Professor - medical
dr. M.L. Houben
  • Cluster D
  • Integral pediatrics patient care

Research Programs

Child Health



Michiel was trained as a medical doctor (2002) and pediatrician (2010) and as a clinical epidemiologist (2009) at the UMC Utrecht. In 2011 he obtained his PhD on his thesis entitled: RSV Bronchiolitis in Healthy Term Infants, Pathogenesis and Prediction. Since 2010 he works as a general pediatrician in the Wilhelmina Children’s Hospital (UMC Utrecht) and since 2014 he is head of the section of general en social pediatrics. He is the pediatrician and coordinator of the 22q11.2 deletion syndrome childhood outward patient clinic and studies the heterogeneity and prognostic factors of this syndrome, in close collaboration with colleagues of other pediatric, surgery, psychiatric, psychology and genetics specialties. He is also involved in several further studies on the healthy term birth (amniotic fluid) cohort from his PhD trajectory.

Side Activities

  • member of Infectious Diseases section and Geneticis and Congenital Anomalies section of Dutch Pediatric Association (NVK secties I&I en Erfelijke en Aangeboren Afwijkingen)

  • 2014-present Chair of Working Group on Development of Guideline for central venous catheter use, WKZ

  • 2013-present Chair of Working Group on Pediatric orthopedic care; quality and routing, WKZ

  • 2013-present Pediatrician member of Working Group on Medication, WKZ

Fellowship and Awards

  • 2011-12 PhD Curriculum of Training Upcoming Leaders in Pediatric Science (TULIPS), competitive selection
  • 2011 NVK Masterclass, Prof Dr B Prakken, Prof Dr HJ Verkade, competitive selection

  • 2007 NVK Young Investigators, award best poster presentation

  • 2005 ESPID Fellowship Award

  • 2000 UMC Utrecht Students’ Scientific meeting, 2nd price for oral presentation

  • 1992 Theoretical Mathematics Olympiads, team competition, national winner

  • 1992 Applied Mathematics Olympiads, team competition, national winner

Research Output (40)

Long-term oncological outcomes of endoscopic full-thickness resection after previous incomplete resection of low-risk T1 CRC (LOCAL-study):study protocol of a national prospective cohort study

Zwager L W, Moons L M G, Farina Sarasqueta A, Laclé M M, Albers S C, Hompes R, Peeters K C M J, Bekkering F C, Boonstra J J, Ter Borg F, Bos P R, Bulte G J, Gielisse E A R, Hazen W L, Ten Hove W R, Houben M H M G, Mundt M W, Nagengast W B, Perk L E, Quispel R, Rietdijk S T, Rando Munoz F J, de Ridder R J J, Schwartz M P, Schreuder R M, Seerden T C J, van der Sluis H, van der Spek B W, Straathof J W A, Terhaar Sive Droste J S, Vlug M S, van de Vrie W, Weusten B L A M, de Wijkerslooth T D, Wolters H J, Fockens P, Dekker E, Bastiaansen B A J, 13 Dec 2022, In: BMC Gastroenterology. 22 , p. 1-12

The Language Profile of Preschool Children With 22q11.2 Deletion Syndrome and the Relationship With Speech Intelligibility

Everaert Emma, Selten Iris, Boerma Tessel, Houben Michiel, Vorstman Jacob, de Wilde Hester, Derksen Desiree, Haverkamp Sarah, Wijnen Frank, Gerrits Ellen 13 Dec 2022, In: American journal of speech-language pathology. 32 , p. 128-144 17 p.

Ocular findings in 22q11.2 deletion syndrome:A systematic literature review and results of a Dutch multicenter study

von Scheibler Emma N M M, van der Valk Bouman Emy S, Nuijts Myrthe A, Bauer Noël J C, Berendschot Tos T J M, Vermeltfoort Pit, Bok Levinus A, van Eeghen Agnies M, Houben Michiel L, van Amelsvoort Thérèse A M J, Boot Erik, van Egmond-Ebbeling Michelle B 12 Nov 2021, In: American Journal of Medical Genetics. Part A. 188 , p. 569-578 10 p.

22q11.2 deletion syndrome as a human model for idiopathic scoliosis

de Reuver Steven, Homans Jelle F., Schlösser Tom P.C., Houben Michiel L., Deeney Vincent F.X., Crowley Terrence B., Stücker Ralf, Pasha Saba, Kruyt Moyo C., McDonald‐mcginn Donna M., Castelein René M. 20 Oct 2021, In: Journal of Clinical medicine. 10 , p. 1-11

Same or different? Language skills of children with 22q11.2 Deletion Syndrome and children with Developmental Language Disorder

Everaert Emma, Selten Iris, Boerma Tessel, Hulshof Merel, Houben ML, Vorstman Jacob, Gerrits Elianne, Wijnen Frank 3 Jun 2021,

Placenta Pathology From Term Born Neonates With Normal or Adverse Outcome

Nikkels Peter Gj, Evers Annemieke Cc, Schuit Ewoud, Brouwers Hens Aa, Bruinse Hein W, Bont Louis, Houben Michiel L, Kwee Anneke 20 Jan 2021, In: Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society. 24 , p. 121-130 10 p.

A normative chart for cognitive development in a genetically selected population

Fiksinski Ania M, Bearden Carrie E, Bassett Anne S, Kahn Rene S, Zinkstok Janneke R, Hooper Stephen R, Tempelaar Wanda, Vorstman Jacob A S, Breetvelt Elemi J, , Houben ML 2021, In: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 47 , p. 1379-1386 8 p.

‘Iedere kinderarts werkt eigenlijk al volgens het MKS’

Houben ML 1 Sep 2020, In: Kinderarts & Samenleving. 2 p.

An exploratory study on Smith Magenis syndrome::differences in weight and lipid profiles between patients with a 17p11.2 deletion and patients with a RAI1 gene mutation

Houben ML 1 Sep 2020, In: Tijdschrift voor Artsen voor Verstandelijk Gehandicapten. 38 , p. 145-150 10 p.

The role of 22q11.2 deletion syndrome in the relationship between congenital heart disease and scoliosis

Homans Jelle F, de Reuver Steven, Heung Tracy, Silversides Candice K, Oechslin Erwin N, Houben Michiel L, McDonald-McGinn Donna M, Kruyt Moyo C, Castelein René M, Bassett Anne S Jun 2020, In: The Spine Journal. 20 , p. 956-963 8 p.

All research output

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