Clinical Epidemiology & trials
Cardiovascular clinical epidemiology conducts scientific research into solutions for the early recognition, prevention and treatment of various cardiovascular conditions among which heart failure, stroke, heart attack, aneurysms, peripheral arterial disease and venous thrombotic conditions. The goal is to delay the vascular aging process during the course of life and thereby reduce the burden of disease due to cardiovascular disease.
Our research follows the DEPTh approach: i.e., research into Diagnosis, Etiology (causes), Prognosis and Therapy. Methods are applied from the total range of statistical and epidemiological study designs, ranging from multi-center randomized controlled studies into the effects of preventive and therapeutic interventions to large and small cohorts, case control and cross-sectional studies into determinants and prognosis of vascular conditions. In our research we closely and intensely collaborate with various disciplines of the Julius Center (e.g., methodology group) and with researchers and clinicians in the UMC Utrecht within Circulatory Health.
Trials
The CHRC stimulates the conduction of clinical trials in order to translate experimental research into patient therapies more efficiently without compromising on quality and patient safety. Trial designs such as Trials within Cohorts (TwiCs), register-based trials and adaptive trials are all possibilities within this field. Contact person is dr. Mira Zuidgeest.