prof. dr. A.D.R. (Alwin) Huitema

Full Professor

  • Clinical Pharmacy

prof. dr. A.D.R. (Alwin) Huitema

Research Programs

Side Activities

  • 2002 - : Member of the Medical Ethical Committee of Netherlands Cancer Institute

    2003 - : Involved in many early clinical trials of novel anticancer agents (not further specified, revenues for Netherlands Cancer Institute)

    2016 - 2018: Member of scientific councel "Stichting Kinderen Kankervrij (KiKa)"

    2017 - : Member of the working group Oncology & Hematology of "Horizonscan geneesmiddelen", ZorgInstituut Nederland

    2018 - : Board member of Dutch Society of Clinical Pharmacology & Biopharmaceutics

Fellowship and Awards

  • 2015 Galenus research prize

    2014 Huizinga penning of the Dutch Association of Hospital Pharmacists

Research Output (173)

The Predictive Value of Low Skeletal Muscle Mass Assessed on Cross-Sectional Imaging for Anti-Cancer Drug Toxicity:A Systematic Review and Meta-Analysis

Huiskamp Laura F J, Chargi Najiba, Devriese Lot A, May Anne M, Huitema Alwin D R, de Bree Remco 23 nov 2020, In: Journal of Clinical medicine. 9 , p. 3780

Therapeutic drug monitoring of imatinib in patients with gastrointestinal stromal tumours - Results from daily clinical practice

IJzerman Nikki S, Groenland Stefanie L, Koenen Anne Miek, Kerst Martijn, van der Graaf Winette T A, Rosing Hilde, Beijnen Jos H, Huitema Alwin D R, Steeghs Neeltje sep 2020, In: European Journal of Cancer. 136 , p. 140-148 9 p.

Cisplatin and carboplatin pharmacokinetics in a pediatric patient with hepatoblastoma receiving peritoneal dialysis

Nijstad A Laura, van Eijkelenburg Natasha K A, Kraal Kathelijne C J M, Meijs Marieke J M, de Kanter Clara T M M, Lilien Marc R, Huitema Alwin D R 20 aug 2020, In: Cancer Chemotherapy and Pharmacology. 86 , p. 445-449 5 p.

Evaluation of Extrapolation Methods to Predict Trough Concentrations to Guide Therapeutic Drug Monitoring of Oral Anticancer Drugs

Janssen Julie M., Dorlo Thomas P.C., Beijnen Jos H., Huitema Alwin D.R. 1 aug 2020, In: Therapeutic drug monitoring. 42 , p. 532-539 8 p.

Exposure-response analyses of abiraterone and its metabolites in real-world patients with metastatic castration-resistant prostate cancer

van Nuland M, Groenland S L, Bergman A M, Steeghs N, Rosing H, Venekamp N, Huitema A D R, Beijnen J H jun 2020, In: Prostate cancer and prostatic diseases. 23 , p. 244-251 8 p.

Prediction of drug exposure in critically ill encephalopathic neonates treated with therapeutic hypothermia based on a pooled population pharmacokinetic analysis of seven drugs and five metabolites

Favié Laurent M A, de Haan Timo R, Bijleveld Yuma A, Rademaker Carin M A, Egberts Toine C G, Nuytemans Debbie H G M, Mathôt Ron A A, Groenendaal Floris, Huitema Alwin D R 28 mei 2020, In: Clinical Pharmacology and Therapeutics. 108 , p. 1098-1106 9 p.

Phase I pharmacological study of continuous chronomodulated capecitabine treatment

Roosendaal Jeroen, Jacobs Bart A W, Pluim Dick, Rosing Hilde, de Vries Niels, van Werkhoven Erik, Nuijen Bastiaan, Beijnen Jos H, Huitema Alwin D R, Schellens Jan H M, Marchetti Serena 7 mei 2020, In: Pharmaceutical Research. 37 10 p.

Phase I study of lapatinib plus trametinib in patients with KRAS-mutant colorectal, non-small cell lung, and pancreatic cancer

Huijberts Sanne C F A, van Geel Robin M J M, van Brummelen Emilie M J, Opdam Frans L, Marchetti Serena, Steeghs Neeltje, Pulleman Saskia, Thijssen Bas, Rosing Hilde, Monkhorst Kim, Huitema Alwin D R, Beijnen Jos H, Bernards René, Schellens Jan H M 1 mei 2020, In: Cancer Chemotherapy and Pharmacology. 85 , p. 917-930 14 p.

Concomitant intake of abiraterone acetate and food to increase pharmacokinetic exposure:real life data from a therapeutic drug monitoring programme

Groenland Stefanie L, van Nuland Merel, Bergman Andries M, de Feijter Jeantine M, Dezentje Vincent O, Rosing Hilde, Beijnen Jos H, Huitema Alwin D R, Steeghs Neeltje, mei 2020, In: European Journal of Cancer. 130 , p. 32-38 7 p.

Measurement of NLG207 (formerly CRLX101) nanoparticle-bound and released camptothecin in human plasma

Schmidt Keith T, Peer Cody J, Huitema Alwin D R, Williams Monique D, Wroblewski Susan, Schellens Jan H M, Madan Ravi A, Figg William D 20 mrt 2020, In: Journal of Pharmaceutical and Biomedical Analysis. 181 , p. 113073

All Research Output (173)