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dr. M. Bartels

Assistant Professor - medical

  • Haematology patient care
  • Hematology/Van Creveldclinic

dr. M. Bartels

Research Programs

Biography

Marije Bartels, MD, PhD is a pediatric hematologist working at the Pediatric Hematology department of the Wilhelmina Children’s Hospital/UMC Utrecht. She has a special interest in inherited bone marrow failure syndromes, and rare anemias. Following her PhD thesis in 2014, she continued her research on epigenomic regulation of myeloid disorders and on the biology of inherited bone marrow failure syndromes with a special focus on Diamond-Blackfan anemia and Severe Congenital Neutropenia.

Marije is an active member of national and international committees concerning bone marrow failure disorders in children (including PNH), and red blood cell pathology.

Side Activities

    • European Diamond Blackfan Consortium (EuroDBA) 

    • Scientific Working Group on Granulocytes and Constitutional Marrow Failure Disordres (European Hematology Association) 

    • Scientific Working Group on Red Cells and Iron Metabolism (European Hematology Association) 

    • Severe Chronic Neutropenia International Registry/Consortium

    • National working committee PNH (paroxsymal nocturnal hemoglobinuria)

    • National working committee bone marrow failure (within  “sectie kinderhematologie”)

    • Medical committee “Villa Pardoes” 

Fellowship and Awards

  • 2013 Wilhelmina Children’s hospital Fund: Leading ladies research stimulation grant €125.000 euro

    2012 American Society of Hematology (ASH) Abstract Achievement Award

     

Research Output (26)

Oxygen gradient ektacytometry-derived biomarkers are associated with vaso-occlusive crises and correlate with treatment response in sickle cell disease

Rab Minke A E, Kanne Celeste K, Bos Jennifer, van Oirschot Brigitte A, Boisson Camille, Houwing Maite E, Gerritsma Jorn, Teske Erik, Renoux Celine, Riedl Jurgen, Schutgens Roger E G, Bartels Marije, Nur Erfan, Joly Philippe, Fort Romain, Cnossen Marjon H, van Wijk Richard, Connes Philippe, van Beers Eduard J, Sheehan Vivien A jan 2021, In: American Journal of Hematology. 96 , p. E29-E32 4 p.

Rivaroxaban compared with standard anticoagulants for the treatment of acute venous thromboembolism in children: a randomised, controlled, phase 3 trial

Male Christoph, Lensing Anthonie W. A., Palumbo Joseph S., Kumar Riten, Nurmeev Ildar, Hege Kerry, Bonnet Damien, Connor Philip, Hooimeijer Helene L., Torres Marcela, Chan Anthony K. C., Kenet Gili, Holzhauer Susanne, Santamaria Amparo, Amedro Pascal, Chalmers Elizabeth, Simioni Paolo, Bhat Rukhmi V., Yee Donald L., Lvova Olga, Beyer-Westendorf Jan, Biss Tina T., Martinelli Ida, Saracco Paola, Peters Marjolein, Kallay Krisztian, Gauger Cynthia A., Massicotte M. Patricia, Young Guy, Pap Akos F., Majumder Madhurima, Smith William T., Heubach Jurgen F., Berkowitz Scott D., Thelen Kirstin, Kubitza Dagmar, Crowther Mark, Prins Martin H., Monagle Paul, , Bartels M jan 2020, In: Lancet haematology. 7 , p. E18-E27

Williams Hematology 10th edition:Erythrocyte Enzyme Disorders

Bartels M, van Beers Eduard, van Wijk Richard 2020, p. 749-784 35 p.

AML Subtype Is a Major Determinant of the Association between Prognostic Gene Expression Signatures and Their Clinical Significance

Wiggers Caroline R M, Baak Mirna L, Sonneveld Edwin, Nieuwenhuis Edward E S, Bartels Marije, Creyghton Menno P 10 sep 2019, In: Cell Reports. 28 , p. 2866-2877.e5

Recognizing a Non-classical Telomeropathy before Hematopoietic Stem Cell Transplantation in Pediatric Patients:A Case Series

Nederlof Iris, Lindemans Caroline A, Bierings Marc B, Mohseny Alexander B, Bresters Dorine, Bartels Marije aug 2019, In: HemaSphere. 3

The Complexity of Genotype-Phenotype Correlations in Hereditary Spherocytosis:A Cohort of 95 Patients: Genotype-Phenotype Correlation in Hereditary Spherocytosis

van Vuren Annelies, van der Zwaag Bert, Huisjes Rick, Lak Nathalie, Bierings Marc, Gerritsen Egbert, van Beers Eduard, Bartels Marije, van Wijk Richard aug 2019, In: HemaSphere. 3

Transcriptomic and Epigenomic Profiling of Histone Deacetylase Inhibitor Treatment Reveals Distinct Gene Regulation Profiles Leading to Impaired Neutrophil Development

Govers Anita M A P, Wiggers Caroline R M, van Boxtel Ruben, Mokry Michal, Nieuwenhuis Edward E S, Creyghton Menno P, Bartels Marije, Coffer Paul J aug 2019, In: HemaSphere. 3

Red Blood Cells:Chasing Interactions

Pretini Virginia, Koenen Mischa H, Kaestner Lars, Fens Marcel H A M, Schiffelers Raymond M, Bartels Marije, Van Wijk Richard 31 jul 2019, In: Frontiers in Physiology. 10

Characterization of the phenotype of human eosinophils and their progenitors in the bone marrow of healthy individuals

Hassani Marwan, van Staveren Selma, van Grinsven Erinke, Bartels Marije, Tesselaar Kiki, Leijte Guus, Kox Mathijs, Pickkers Peter, Vrisekoop Nienke, Koenderman Leo 17 mei 2019, In: Haematologica. 105 , p. e52-e56 5 p.

Epigenetic drug screen identifies the histone deacetylase inhibitor NSC3852 as a potential novel drug for the treatment of pediatric acute myeloid leukemia

Wiggers Caroline R M, Govers Anita M A P, Lelieveld Daphne, Egan David A, Zwaan C Michel, Sonneveld Edwin, Coffer Paul J, Bartels Marije 1 mei 2019, In: Pediatric Blood & Cancer. 66

All Research Output (26)