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Dr. E.H. Gort

Internist-Oncoloog

Wetenschappelijk onderzoek en publicaties uitklapper, klik om te openen

Proefschrift aan de Universtiteit Utrecht (2008)

Publicaties

Gort EH, Elias SG, Elkhuizen PHM, Visser O and Linn SC;

Retrospective analysis of the effect on overall survival of radiotherapy and chemotherapy sequence as treatment for primary breast cancer.

J Clin Oncol 29: 2011 (suppl; abstr 1127)

 

Gort EH, Suijkerbuijk KPM, Roothaan S, Raman V, Vooijs M, van der Wall E, van Diest PJ;

Methylation of the TWIST1 promoter, TWIST1 mRNA levels, and immunohistochemical expression of TWIST1 in breast cancer.

Cancer Epidemiol Biomarkers Prev 2008 Dec;17(12):3325-3330.

 

Groot AJ, Gort EH, van der Wall E, van Diest PJ, Vooijs M;

Conditional inactivation of HIF-1 using intrabodies.

Cellular Oncology 2008;30(5):397-409.

 

Gort EH, Groot AJ, van der Wall E, van Diest PJ, Vooijs M;

Review; Hypoxic Regulation of Metastasis via Hypoxia-inducible Factors.

Current Molecular Medicine 2008 Feb;8(1):60-7. Review.

Gort EH, Horrée N, van der Groep P, Heintz APM, Vooijs M, van Diest PJ;

Hypoxia-inducible factor-1 alpha is essential for hypoxic induction of p27 in endometrioid endometrial carcinoma.

 

Journal of Pathology. 2008 Jan;214(1):38-45.

Gort EH, van Haaften G, Verlaan I, Groot A, Plasterk RHA, Shvarts A, Suijkerbuijk KP, van Laar T, van der Wall E, Raman V, van Diest PJ, Tijsterman M, Vooijs M;

The basic helix-loop-helix transcription factor TWIST1 is a direct target of Hypoxia-inducible factor-2alpha.

 

Oncogene. 2008 Mar 6;27(11):1501-10. Epub 2007 Sep 17

Cuppen E, Gort EH, Hazendonk E, Mudde J, Nijman IJ, Guryev V, Plasterk RHA;

Efficient target-selected mutagenesis in Caenorhabditis elegans: towards a knockout for every gene.

Genome Res. 2007 May;17(5):649-58. Epub 2007 Apr 6.

 

Gort EH, Groot AJ, Derks van de Ven TLP, van der Groep P, Verlaan I, van Laar T, van Diest PJ, van der Wall E, Shvarts A;

Hypoxia-inducible factor-1alpha expression requires PI 3-kinase activity and correlates with Akt1 phosphorylation in invasive breast carcinomas.

Oncogene. 2006 Oct 5;25(45):6123-7. Epub 2006 May 8.

 

Groot AJ, Verheesen P, Westerlaken EJ, Gort EH, van der Groep P, Bovenschen N, van der Wall E, van Diest PJ, Shvarts A;

Identification by phage display of single-domain antibody fragments specific for the ODD domain in HIF-1a, Lab Invest. 2006 Apr;86(4):345-56.