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dr. H.L. (Helen) Leavis

dr. H.L. (Helen) Leavis

Associate Professor - medical

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Research Output (79)

Phenotypic variability in patients with ADA2 deficiency due to identical homozygous R169Q mutations

van Montfrans Joris M., Hartman Esther A R, Braun Kees P J, Hennekam Eric A M, Hak Elisabeth A., Nederkoorn Paul J., Westendorp Willeke F., Bredius Robbert G M, Kollen Wouter J W, Schölvinck Elisabeth H., Elizabeth Legger G., Meyts Isabelle, Liston Adrian, Lichtenbelt Klaske D., Giltay Jacques C., Van Haaften Gijs, De Vries Simons Gaby M., Leavis Helen, Sanders Cornelis J G, Bierings Marc B., Nierkens Stefan, Van Gijn Marielle E. 1 May 2016, In: Rheumatology (Oxford, England). 55 , p. 902-910 9 p.

Allogeneic stem cell transplantation in a patient with myelodysplastic syndrome and polyarteritis nodosa:a case report and systematic review

Stavenga Mirte, Leavis Helen L., de Witte Theo M., Raymakers Reinier A.P. 1 Mar 2016, In: Annals of Hematology. 95 , p. 645-647 3 p.

Synergistic activity of a short lipidated antimicrobial peptide (lipoAMP) and colistin or tobramycin against Pseudomonas aeruginosa from cystic fibrosis patients

De Gier Martin G., Bauke Albada H., Josten Michaele, Willems Rob, Leavis Helen, Van Mansveld Rosa, Paganelli Fernanda L., Dekker Bertie, Lammers Jan Willem J, Sahl Hans Georg, Metzler-Nolte Nils 2016, In: MedChemComm. 7 , p. 148-156 9 p.

Loss-of-function mutations in TNFAIP3 leading to A20 haploinsufficiency cause an early-onset autoinflammatory disease

Zhou Qing, Wang Hongying, Schwartz Daniella M, Stoffels Monique, Park Yong Hwan, Zhang Yuan, Yang Dan, Demirkaya Erkan, Takeuchi Masaki, Tsai Wanxia Li, Lyons Jonathan J, Yu Xiaomin, Ouyang Claudia, Chen Celeste, Chin David T, Zaal Kristien, Chandrasekharappa Settara C, P Hanson Eric, Yu Zhen, Mullikin James C, Hasni Sarfaraz A, Wertz Ingrid E, Ombrello Amanda K, Stone Deborah L, Hoffmann Patrycja, Jones Anne, Barham Beverly K, Leavis Helen L, van Royen Annet , Sibley Cailin, Batu Ezgi D, Gül Ahmet, Siegel Richard M, Boehm Manfred, Milner Joshua D, Ozen Seza, Gadina Massimo, Chae JaeJin, Laxer Ronald M, Kastner Daniel L, Aksentijevich Ivona 7 Dec 2015, In: Nature Genetics. 48 , p. 67–73

Distinct SagA from Hospital-Associated Clade A1 Enterococcus faecium Strains Contributes to Biofilm Formation

Paganelli F. L., de Been M., Braat J. C., Hoogenboezem T., Vink C., Bayjanov J., Rogers M. R. C., Huebner J., Bonten M. J. M., Willems R. J. L., Leavis H. L. Oct 2015, In: Applied and Environmental Microbiology. 81 , p. 6873-6882 10 p.

Phenotypic variability in patients with ADA2 deficiency due to identical homozygous R169Q mutations

Van Montfrans J., Hartman E., Braun K., Hennekam F., Hak A., Nederkoorn P., Westendorp W., Bredius R., Kollen W., Scholvinck E., Legger G., Meyts I., Liston A., Lichtenbelt K., Giltay J., Van Haaften G., De Vries Simons G., Leavis H., Nierkens S., Sanders C., Van Gijn M. 28 Sep 2015, In: Pediatric Rheumatology. 13

Implementation of targeted NGS based pid screening for routine diagnostic use

van Montfrans J.M., van de Corput L., van Zon P.H.A, Elferink M.G., Frenkel J., Leavis H., Ellerbroek P.M., van Royen-Kerkhof A., Janssen W., Boes M., Ploos van Amstel H.K., van Gijn M.E. 29 Oct 2014,

Implementation of Targeted NGS Based PID Screening for Routine Diagnostic Use

van Montfrans J., van de Corput L., van Zon P., Elferink M. G., Harts W., Frenkel J., Leavis H., Ellerbroek P., van Royen-Kerkhof A., Janssen W., Boes M., van Amstel J. Ploos, Gijn M. E. Oct 2014, In: Journal of Clinical Immunology. 34 , p. S379-S379 1 p.

Enterococcus faecium biofilm formation:identification of major autolysin AtlAEfm, associated Acm surface localization, and AtlAEfm-independent extracellular DNA Release

Paganelli Fernanda L, Willems Rob J L, Jansen Pamela, Hendrickx Antoni, Zhang Xinglin, Bonten Marc J M, Leavis Helen L 16 Apr 2013, In: MBio [E]. 4 1 p.

The Enterococcus faecium enterococcal biofilm regulator, EbrB, regulates the esp operon and is implicated in biofilm formation and intestinal colonization

Top J., Paganelli L.F., Zhang X., van Schaik W., Leavis H.L., van Luit-Asbroek M., van der Poll T., Leendertse M., Bonten M.J.M., Willems R.J.L. 2013, In: PLoS ONE [E]. 8 , p. e65224 1 p.

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