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prof. dr. W.A. (Wilton A) van Klei

prof. dr. W.A. (Wilton A) van Klei

Full Professor
prof. dr. W.A. (Wilton A) van Klei
  • Anesthesiology

Research Programs

Circulatory Health

Biography

Biography

Wilton van Klei received his PhD in 2002 and completed his postgraduate training as anesthesiologist in the Netherlands (2006. After that he did a clinical and research fellowship in perioperative medicine (Ottawa, Ontario, 2007). He returned to the Netherlands to complete a fellowship in cardiothoracic anesthesia (2009), including training in TEE. From 2007 till 2012, he was the Medical Director of the Outpatient Preoperative Evaluation Clinic of the UMC Utrecht. Subsequently, he was the Chair of the Department of Anesthesiology and the Director Research and Education of the Division of Anesthesiology, Intensive Care and Emergency Medicine of the UMC Utrecht (2013-2021). Curently, his primary affiliation is at the University Health Network Toronto / University of Toronto, but he holds a small appointment as a research professor at the UMC Utrecht.

 

His interests focus on improving care for high-risk surgical patients, and involve collaborations with cardiologists, surgeons, clinical chemists, and epidemiologists within the UMC Utrecht’s Circulatory Health research programme. He is supervising several PhD students on clinical research projects in the field of cardiovascular perioperative medicine. Most projects aim to unravel further the etiology, detection and treatment of asymptomatic myocardial injury after surgery. He considers hisself a specialist in perioperative medicine.
Perioperative medicine starts before surgery with a preanesthesia assessment and currently often ends with the patient leaving the recovery room, except for a responsibility for postoperative pain management. However, anesthesiologists should be involved not only in pain management, but also in providing postoperative care on general wards, monitoring vital functions and monitoring for complications likely to be related to surgery and anesthesia. In fact, anesthesiologists should extend what they are doing in the operating room to the surgical floor in order to improve patient outcomes. He is working towards this goal by initiating research in those areas where evidence for optimal treatment is absent.

Side Activities

No side activities

Fellowship and Awards

2011 Research Award of the International Anesthesia Research Society (IARS)

Research Output (208)

Protocol ter preventie van perioperatieve pulmonale complicaties

Miggelbrink Lynn Ann, Marsman Marije, Senff Jasper R., van Waes Judith A.R., Bronsveld Inez, van Klei Wilton, Kappen Teus 20 Oct 2022, In: Nederlands Tijdschrift voor Geneeskunde. 166

Associations between intraoperative hypotension, duration of surgery and postoperative myocardial injury after noncardiac surgery:a retrospective single-centre cohort study

Wesselink Esther M., Wagemakers Sjors H., van Waes Judith A.R., Wanderer Jonathan P., van Klei Wilton A., Kappen Teus H. Oct 2022, In: British Journal of Anaesthesia. 129 , p. 487-496 10 p.

Definitions of low cardiac output syndrome after cardiac surgery and their effect on the incidence of intraoperative LCOS:A literature review and cohort study

Schoonen Anna, van Klei Wilton A, van Wolfswinkel Leo, van Loon Kim 29 Sep 2022, In: Frontiers in cardiovascular medicine. 9

Outlying End-Tidal Carbon Dioxide During General Anesthesia Is Associated With Postoperative Pulmonary Complications:A Multicenter Retrospective Observational Study From US Hospitals Between 2010 and 2017

Akkermans Annemarie, Van Waes Judith A., Kheterpal Sachin, Pasma Wietze, Saager Leif, Thompson Aleda, Van Klei Wilton A. 1 Aug 2022, In: Anesthesia and Analgesia. 135 , p. 341-353 13 p.

Cochrane corner:Biomarkers to improve preoperative prediction of major cardiac outcomes after non-cardiac surgery

Vernooij Lisette M, van Klei Wilton A, Moons Karel Gm, van Waes Judith Ar, Damen Johanna Aag 5 Jul 2022, In: Heart (British Cardiac Society). 108 , p. 1257-1259 3 p.

Critical oxygen delivery threshold during cardiopulmonary bypass in older cardiac surgery patients with increased frailty risk

Smoor Rosa M., Van Dongen Eric P.A., Verwijmeren Lisa, Schreurs Inge A.A.M., Vernooij Lisette M., Van Klei Wilton A., Noordzij Peter G. 1 Mar 2022, In: European Journal of Cardio-thoracic Surgery. 61 , p. 685-692 8 p.

The comparative and added prognostic value of biomarkers to the Revised Cardiac Risk Index for preoperative prediction of major adverse cardiac events and all-cause mortality in patients who undergo noncardiac surgery

Vernooij Lisette M, van Klei Wilton A, Moons Karel Gm, Takada Toshihiko, van Waes Judith, Damen Johanna Aag 21 Dec 2021, In: The Cochrane database of systematic reviews. 2021 , p. 1-439

Intraoperative hypotension and delirium among older adults undergoing transcatheter aortic valve replacement

Wesselink Esther M., Abawi Masieh, Kooistra Nynke H. M., Kappen Teus H., Agostoni Pierfrancesco, Emmelot-Vonk Marielle, Pasma Wietze, Klei Wilton A., Jaarsveld Romy C., Dongen Charlotte S., Doevendans Pieter P. A. F. M., Slooter Arjen J. C., Stella Pieter R. Nov 2021, In: Journal of the American Geriatrics Society. 69 , p. 3177-3185 9 p.

Gastric fluid volume in adults after implementation of a liberal fasting policy:a prospective cohort study

Marsman Marije, Pouw Niels, Moons Leon M.G., van Klei Wilton A., Kappen Teus H. Sep 2021, In: British Journal of Anaesthesia. 127 , p. e85-e87

Supervision, Interprofessional Collaboration, and Patient Safety in Intensive Care Units during the COVID-19 Pandemic

Hennus Marije P, Young John Q, Hennessy Martina, Friedman Karen A, de Vries Bas, Hoff Reinier G, O'Connor Enda, Patterson Aileen, Curley Gerard, Thakker Krima, van Dam Marjel, van Dijk Diederik, van Klei Wilton A, Ten Cate Olle Sep 2021, In: ATS scholar. 2 , p. 397-414 18 p.

All research output

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