prof. dr. P. (Pim) van der Harst
prof. dr. P. (Pim) van der Harst
- Department of Cardiology
Research Programs
Biography
Biography
I am an interventional cardiologist and scientist and head of the department of cardiology of the University Medical Center Utrecht. My clinical work includes the percutaneous treatment of obstructive coronary artery disease, including acute myocardial infarction. My translational research focusses on the analysis of big and complex data (e.g. genetic, ehr, imaging), including the use of machine learning and cloud computing, to improve our understanding and the early detection of coronary artery disease and heart failure. To this end we use large population based cohorts, including the Dutch PREVEND and LifeLine cohorts and the UK Biobank. Data on my "omics" research can be found our my website: www.cardiomics.net In my clinical translational research I am also working on advanced image analysis, device interventions, machine learning, deep learning, and e/m Health to further improve and personalize care for our patients. Currently ongoing diagnostic imaging studies in include the REPLACE-IT (replacement of invasive coronary angiography) and the EARLY-SYNERGY (early detection of obstructive coronary artery disease; www.early-synergy.nl) studies. Currently interventional studies include the GIPS-IV, AXES and MRI-MC studies. Many of my projects based on collaborations with the most influential and creative individuals and research groups in the world.
Side Activities
2020- honorary appointment Departmentof Cardiology, University Medical Center Groningen
2020- National member of Scientific Advisory Board LifeLiens Cohort Study
2019- Member of Science & Innovation Committee, Dutch Society of Cardiology
2019- Member of the Scientific Counsel of the Dutch Heart Registration (NHR)
2019- Nucleus member of the Council on Cardiovascular Genomics, European Society of Cardiology
2018- Member of the Workgroup Acute Coronary Syndrome, Dutch Society of Cardiology
2020-2021 Member of the Supervisory Board Netherlands Heart Institute
2017-2021 Co-founder and manager non-medical affairs Mijnhuisarts B.V. (primary care facility province of Groningen)
2017- Director and owner of the holding Generalis Procuratio B.V.
2016-2020 Local member of Scientific Advisory Board LifeLines Cohort Study, LifeLines B.V.
2015-2018 co-organizer & member of the Programing Committee Netherlands Heart Days
2015-2015 Member of the Scientific Sessions Programing Committee, American Heart Association
2014- Member of the Workgroup Interventional Cardiology, Dutch Society of Cardiology
2010-2015 Associate Editor European Journal of Heart Failure
2010-2016 Associate Editor BMC Medical Genetics
2010-2012 member of grant committee Netherlands Heart Foundation
2009-2018 Honorary appointment Department of Cardiovascular Sciences, University of Leicester, UK
2008-2008 Academic Editor of medical journal PLoS Medicine
2008-2012 Editorial Advisory Panel of medical journal Clinical Science
Ad-hoc reviewer for medical journals (including, but not limited to Lancet, Nat Genet, JAMA, PLoS Med, Circulation, Circ Res, J Am Coll Cardiol, Arterioscler Thromb Vasc Biol, Hypertension, Eur Heart J, Hum Mol Genet)
Ad-hoc grant reviewer (including but not limited to; Netherlands Heart Foundation; Netherlands Organisation for Scientific Research (NWO, Netherlands); The Research Foundation Flanders (FWO, Belgium); Medical Research Councel (MRC, South Africa); Danish Councel for Independent Research (FI, Denmark); National Center of Science and Technology Evaluation (Ministry of Education and Science, Republic of Kazakhstan); Heart Research UK (UK).
Fellowship and Awards
Awards
| 2015 |
Winner of Humanimal – One Health Innovation Challenge 2015 with the Durrer Center (of which I was Chief Scientific Officer). Price for “Best Professional Idea Flevoland” for our Open One Health Biobank proposal (€ 50,000.--) |
|---|---|
| 2013 | Scientific Excellence Award from the Board of the UMCG (€ 100,000.--) |
| 2010 | Excellence Award from the Netherlands Foundation for Cardiovascular Excellence for Scientific, Clinical and Presenting Excellence (€ 50,000.--) |
Fellowships
| 2012 | NWO Clinical Fellowship (90.700.441); Systems and functional genomics strategies to identify novel vulnerability genes for heart failure. €160,000.-- |
| 2007 | VENI Fellowship (916.76.170) of the Innovational Research Incentives Scheme of the Netherlands Organization for Scientific Research (NWO); Telomere length in cardiovascular disease; differential expression and prognostic value (€ 248,000.--) |
| 2008 | ICIN Fellowship (€ 45,000.--) of the Interuniversity Cardiology Institute of the Netherlands |
Research Output (494)
Young William J et al. 14 Mar 2023, In: Nature Communications. 14 16 p.
van Hemert Nicole D., Voskuil Michiel, Rozemeijer Rik, Kraaijeveld Adriaan O., Rittersma Saskia Z., Leenders Geert E.H., Stein Mèra, Frambach Peter, van der Harst Pim, Agostoni Pierfrancesco, Stella Pieter R., 18 Jan 2023, In: Catheterization and Cardiovascular Interventions. 101 , p. 505-510 6 p.
Kanoni Stavroula et al. 27 Dec 2022, In: Genome Biology. 23 , p. 1-42
van Hemert Nicole D., Stella Pieter R., Rozemeijer Rik, Stein Mèra, Frambach Peter, Kraaijeveld Adriaan O., Rittersma Saskia Z., Meijs Timion A., Leenders Geert E.H., van der Harst Pim, Agostoni Pierfrancesco, Voskuil Michiel, Dec 2022, In: American Heart Journal Plus: Cardiology Research and Practice. 24 7 p.
Wouters Philippe C, van de Leur Rutger R, Vessies Melle B, van Stipdonk Antonius M W, Ghossein Mohammed A, Hassink Rutger J, Doevendans Pieter A, van der Harst Pim, Maass Alexander H, Prinzen Frits W, Vernooy Kevin, Meine Mathias, van Es René 7 Nov 2022, In: European heart journal. 44 , p. 680-692 13 p.
Shi Canxia, Aboumsallem Joseph Pierre, Suthahar Navin, de Graaf Aniek O, Jansen Joop H, van Zeventer Isabelle A, Bracun Valentina, de Wit Sanne, Screever Elles M, van den Berg Pieter F, Meijers Wouter C, Gansevoort Ron T, Bakker Stephan J L, van der Harst Pim, Silljé Herman H W, Huls Gerwin, de Boer Rudolf A 11 Oct 2022, In: European Journal of Heart Failure. 25 , p. 4-13 10 p.
Yengo Loïc, Vedantam Sailaja, Marouli Eirini, Sidorenko Julia, Bartell Eric, Sakaue Saori, Graff Marielisa, Eliasen Anders U, Jiang Yunxuan, Raghavan Sridharan, Miao Jenkai, Arias Joshua D, Graham Sarah E, Mukamel Ronen E, Spracklen Cassandra N, Yin Xianyong, Chen Shyh-Huei, Ferreira Teresa, Highland Heather H, Ji Yingjie, Karaderi Tugce, Lin Kuang, Lüll Kreete, Malden Deborah E, Medina-Gomez Carolina, Machado Moara, Moore Amy, Rüeger Sina, Sim Xueling, Vrieze Scott, Ahluwalia Tarunveer S, Akiyama Masato, Allison Matthew A, Alvarez Marcus, Andersen Mette K, Ani Alireza, Appadurai Vivek, Arbeeva Liubov, Bhaskar Seema, Bielak Lawrence F, Bollepalli Sailalitha, Bonnycastle Lori L, Bork-Jensen Jette, van der Laan Sander W, van Setten Jessica, Asselbergs Folkert W, de Borst Gert J, de Kleijn Dominique P V, Kraaijeveld Adriaan, van der Harst Pim, Oct 2022, In: Nature. 610 , p. 704-712 9 p.
Rimbert Antoine, Yeung Ming W, Dalila Nawar, Thio Chris H L, Yu Haojie, Loaiza Natalia, Oldoni Federico, van der Graaf Adriaan, Wang Siqi, Said M Abdullah, Blauw Lisanne L, Girardeau Aurore, Bray Lise, Caillaud Amandine, Bloks Vincent W, Marrec Marie, Moulin Philippe, Rensen Patrick C N, van de Sluis Bart, Snieder Harold, Di Filippo Mathilde, van der Harst Pim, Tybjaerg-Hansen Anne, Zimmerman Philip, Cariou Bertrand, Kuivenhoven Jan Albert Oct 2022, In: Arteriosclerosis, Thrombosis, and Vascular Biology. 42 , p. 1262-1271 10 p.
Yeung Ming Wai, van der Harst Pim, Verweij Niek 16 Sep 2022, In: STAR protocols. 3
Young William J et al. 1 Sep 2022, In: Nature Communications. 13