prof. dr. M. (Marry) van den Heuvel-Eibrink

prof. dr. M. (Marry) van den Heuvel-Eibrink

Full Professor
  • Speerpunt
  • Medical Management

Research Programs



MD, PhD Professor translational Pediatric Oncology.

Since 2015, working in the Princess Maxima Center for Pediatric Oncology, and responsible for the now established centralized care and translational research program for all children with renal tumors and on the identification of (genetic) determinants direct and late toxicity.
Since 2016 Medical director of the late effects clinics in the Princess Maxima Center for Pediatric Oncology, Utrecht, the Netherlands.

Decidated to translational research in pediatric oncology, with a special focus on myeloid malignancies, renal tumors and the (genetic) variation of early and late toxicity of childhood cancer.

Side Activities

(Inter)national Boards/Committees/Memberships

  • Dutch Pediatric Association (NVK), since 1991 (member)

  • Dutch Society of Oncology, NVvO, 1993- onwards (member)

  • Dutch Hematology Association (NVvH), since 1995 (member)

  • International Society of Pediatric Oncology (SIOP), since 1996 (member)

  • European Hematology Association (EHA), since 1998 (member)

  • American Society of Hematology (ASH), since 1998 (member)

  • EWOG-MDS group 1999-onwards (member)

  • Dutch Childhood Oncology Group (DCOG) Renal tumor committee 2000 – 2008 (member), 2008 – onwards (chair)

  • I-BFM-AML committee, 2000-onwards (member)

  • DCOG MDS protocol committee, 2003-onwards (chair)

  • Scientific Board of EWOG MDS, 2005 – 2011 (member), 2011 – 2017 (chair)

  • Steering committee DCOG-LATER committee, 2006 – onwards (member)

  • Advisory Board of the International JMML Foundation, 2007- onwards (member)

  • DCOG Disease Committee Bone Marrow Failure and MDS, 2008-onwards (member)

  • SIOP Scientific Programs Advisory Committee(SPAC), 2008-onwards (contributor)

  • DCOG Steering committee for Late effects, 2009- onwards (member)

  • Steering CIE SIOP-RTSG, since 2009 (member)

  • Advisory Board of the DCOG (Raad van Toezicht), 2014 – onwards (member)

  • Organizing committee of annual meeting of the European Hematology Association(EHA), SPC 2014, 2015, 2016 (member)

  • International Steering Committee for renal tumors (SIOP RTSG), 2014- onwards (member and co-chair)

  • Scientific EHA symposium board (SPC) 2014-2017 (member)

  • SIOP scientific CIE, October 2017-2020 (member)

  • Member SIOP-e (member)

  • PanCare (member)


Editorial Board

  • European J of Cancer

  • Pediatric Blood and cancer

  • Journal of Pediatric Endocrinology



  • Pediatric Blood and Cancer

  • Haematologica

  • J of Pediatric Biochemistry

  • Clinical Cancer Research

  • Leukaemia Research

  • J Ped Hem Onc

  • Clin Cancer Research

  • Leukaemia

  • British J of Hematology

  • J of supportive care in Cancer

  • European J of Endocrinology

  • Cancer

  • Am J of Blood

  • Eur J of Cancer

  • Lancet Oncology

  • BMC

  • JCO


Research Output (227)

The Value of IgM Memory B-Cells in the Assessment of Splenic Function in Childhood Cancer Survivors at Risk for Splenic Dysfunction:A DCCSS-LATER Study

Houtman Bente M, Walraven Iris, de Grouw Elke, van der Maazen Richard W M, Kremer Leontien C M, van Dulmen-den Broeder Eline, van den Heuvel-Eibrink Marry M, Tissing Wim J E, Bresters Dorine, van der Pal Helena J H, de Vries Andrica C H, Louwerens Marloes, van der Heiden-van der Loo Margriet, Neggers Sebastian J C, Janssens Geert O, Blijlevens Nicole M A, Lambeck Annechien J A, Preijers Frank, Loonen Jacqueline J 20 Oct 2023, In: Journal of Immunology Research. 2023 8 p.

Prevalence, risk factors and optimal way to determine overweight, obesity and morbid obesity, in the first Dutch cohort of 2,338 long-term survivors of childhood cancer:a DCCSS-LATER study

Pluimakers V G, van Atteveld J E, de Winter D T C, Bolier M, Fiocco M, Nievelstein R A J, Janssens G O R, Bresters D, van der Heiden-van der Loo M, de Vries A C H, Louwerens M, van der Pal H J, Pluijm S M F, Ronckers C M, Versluijs A B, Kremer L C M, Loonen J J, van Dulmen-den Broeder E, Tissing W J E, van Santen H M, van den Heuvel-Eibrink M M, Neggers S J C M M 14 Oct 2023, In: European Journal of Endocrinology. 189 , p. 495-507 13 p.

MRI-based inter- and intrafraction motion analysis of the pancreatic tail and spleen as preparation for adaptive MRI-guided radiotherapy in neuroblastoma

Van Ommen Fasco, le Quellenec Gaelle A T, Willemsen-Bosman Mirjam E, van Noesel Max M, van den Heuvel-Eibrink Marry M, Seravalli Enrica, Kroon Petra S, Janssens Geert O 2 Oct 2023, In: Radiation Oncology [E]. 18

Extensive Cardiac Function Analyses Using Contemporary Echocardiography in Childhood Cancer Survivors:A DCCSS LATER Study

Merkx Remy, Leerink Jan M, Feijen E Lieke A M, de Baat Esmée C, Bellersen Louise, Bresters Dorine, van Dalen Elvira C, van Dulmen-den Broeder Eline, van der Heiden-van der Loo Margriet, van den Heuvel-Eibrink Marry M, Kok Judith L, Louwerens Marloes, Maas Angela H E M, Neggers Sebastian J C M M, Ronckers Cécile M, Teepen Jop C, Teske Arco J, Tissing Wim J E, de Vries Andrica C H, Weijers Gert, de Korte Chris L, Loonen Jacqueline, Mavinkurve-Groothuis Annelies M C, van der Pal Helena J H, Kremer Leontien C M, Kok Wouter E M, Kapusta Livia, Aug 2023, In: J AM Coll Cardiol CardioOnc. 5 , p. 472-485 14 p.

Hydrocortisone to reduce dexamethasone-induced neurobehavioral side-effects in children with acute lymphoblastic leukaemia—results of a double-blind, randomised controlled trial with cross-over design

van Hulst Annelienke M., van den Akker Erica L.T., Verwaaijen Emma J., Fiocco Marta, Rensen Niki, van Litsenburg Raphaële R.L., Pluijm Saskia M.F., Zwaan C. Michel, van Santen Hanneke M., Pieters Rob, Evers Andrea W.M., Grootenhuis Martha A., van den Heuvel-Eibrink Marry M. Jul 2023, In: European Journal of Cancer. 187 , p. 124-133 10 p.

Long term safety of growth hormone replacement therapy in survivors of cancer and tumors of the pituitary region

Bolier Melissa, Van der Lelij Aart-Jan, Maxima Princess, van den Heuvel-Eibrink Marry M, Neggers Sebastian J C M M 1 Apr 2023, In: Endocrine-related cancer. 30

Radiologic versus Segmentation Measurements to Quantify Wilms Tumor Volume on MRI in Pediatric Patients

Buser Myrthe A D, van der Steeg Alida F W, Wijnen Marc H W A, Fitski Matthijs, van Tinteren Harm, van den Heuvel-Eibrink Marry M, Littooij Annemieke S, van der Velden Bas H M 1 Apr 2023, In: Cancers. 15 11 p.

Frailty and sarcopenia within the earliest national Dutch childhood cancer survivor cohort (DCCSS-LATER):a cross-sectional study

van Atteveld Jenneke E., de Winter Demi T.C., Pluimakers Vincent G., Fiocco Marta, Nievelstein Rutger A.J., Hobbelink Monique G.G., Kremer Leontien C.M., Grootenhuis Martha A., Maurice-Stam Heleen, Tissing Wim J.E., de Vries Andrica C.H., Loonen Jacqueline J., van Dulmen-den Broeder Eline, van der Pal Helena J.H., Pluijm Saskia M.F., van der Heiden-van der Loo Margriet, Versluijs A. Birgitta, Louwerens Marloes, Bresters Dorine, van Santen Hanneke M., Hoefer Imo, van den Berg Sjoerd A.A., den Hartogh Jaap, Hoeijmakers Jan H.J., Neggers Sebastian J.C.M.M., van den Heuvel-Eibrink Marry M., Apr 2023, In: The Lancet Healthy Longevity. 4 , p. e155-e165

Experiences of Female Childhood Cancer Patients and Survivors Regarding Information and Counselling on Gonadotoxicity Risk and Fertility Preservation at Diagnosis:A Systematic Review

Clasen Nikita H Z, van der Perk M E Madeleine, Neggers Sebastian J C M M, Bos Annelies M E, van den Heuvel-Eibrink Marry M Apr 2023, In: Cancers. 15

Thyroid dysfunction during treatment with systemic antineoplastic therapy for childhood cancer:a systematic review

van der Leij Stephanie, Lebbink Chantal A, Lentjes Eef Gwm, Tissing Wim Je, Stuart Annemarie Verrijn, van den Heuvel-Eibrink Marry M, van Santen Hanneke M, van Dalen Elvira C 10 Mar 2023, In: Critical Reviews in Oncology/Hematology. 184

All research output

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