prof. dr. L.H. (Leonard) van den Berg

prof. dr. L.H. (Leonard) van den Berg

Full Professor

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Research Output (631)

Frequency of euthanasia, factors associated with end-of-life practices, and quality of end-of-life care in patients with amyotrophic lateral sclerosis in the Netherlands:a population-based cohort study

van Eenennaam Remko M, Kruithof Willeke, Beelen Anita, Bakker Leonhard A, van Eijk Ruben P A, Maessen Maud, Baardman Joost F, Visser-Meily Johanna M A, Veldink Jan H, van den Berg Leonard H Jul 2023, In: The Lancet. Neurology. 22 , p. 591-601 11 p.

Development of a Rasch-Built Amyotrophic Lateral Sclerosis Impairment Multidomain Scale to Measure Disease Progression in ALS

de Jongh Adriaan D, van Eijk Ruben P A, Bakker Leonhard A, Bunte Tommy M, Beelen Anita, van der Meijden Conny, van Es Michael A, Visser-Meily Johanna, Kruitwagen Esther T, Veldink Jan H, van den Berg Leonard H 13 Jun 2023, In: Neurology. 101 , p. E602-E612

Courage-als:a randomized, double-blind phase 3 study designed to improve participant experience and increase the probability of success

Shefner Jeremy M, Al-Chalabi Ammar, Andrews Jinsy A, Chio Adriano, De Carvalho Mamede, Cockroft Bettina M, Corcia Philippe, Couratier Philippe, Cudkowicz Merit E, Genge Angela, Hardiman Orla, Heiman-Patterson Terry, Henderson Robert D, Ingre Caroline, Jackson Carlayne E, Johnston Wendy, Lechtzin Noah, Ludolph Albert, Maragakis Nicholas J, Miller Timothy M, Mora Pardina Jesus S, Petri Susanne, Simmons Zachary, Van Den Berg Leonard H, Zinman Lorne, Kupfer Stuart, Malik Fady I, Meng Lisa, Simkins Tyrell J, Wei Jenny, Wolff Andrew A, Rudnicki Stacy A 30 May 2023, In: Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration. 24 , p. 523-534 12 p.

PRECISION ALS-an integrated pan European patient data platform for ALS

McFarlane Robert, Galvin Miriam, Heverin Mark, Mac Domhnaill Éanna, Murray Deirdre, Meldrum Dara, Bede Peter, Bolger Anthony, Hederman Lucy, Impey Sinéad, Stephens Gaye, O'Meara Ciara, Wade Vincent, Al-Chalabi Ammar, Chiò Adriano, Corcia Phillippe, van Damme Philip, Ingre Caroline, McDermott Christopher, Povedanos Monica, van den Berg Leonard, Hardiman Orla 23 May 2023, In: Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration. 24 , p. 389-393 5 p.

Development and Evaluation of a Simulation-Based Algorithm to Optimize the Planning of Interim Analyses for Clinical Trials in ALS

van Unnik Jordi W J, Nikolakopoulos Stavros, Eijkemans Marinus J C, Gonzalez-Bermejo Jésus, Bruneteau Gaelle, Morelot-Panzini Capucine, van den Berg Leonard H, Cudkowicz Merit E, McDermott Christopher J, Similowski Thomas, van Eijk Ruben P A 21 Apr 2023, In: Neurology. 100 , p. e2398-e2408

Physical training and high protein diet improved muscle strength, parent-reported fatigue and physical quality of life in children with Pompe disease

Scheffers L E, Somers O C, Dulfer K, Dieleman G C, Walet S, van der Giessen L J, Ploeg A T, van den Hout J M P, van den Berg L E, 1 Apr 2023, In: Journal of Inherited Metabolic Disease. 46 , p. 605-617 13 p.

The contribution of Neanderthal introgression and natural selection to neurodegenerative diseases

Chen Zhongbo, Reynolds Regina H, Pardiñas Antonio F, Gagliano Taliun Sarah A, van Rheenen Wouter, Lin Kuang, Shatunov Aleksey, Gustavsson Emil K, Fogh Isabella, Jones Ashley R, Robberecht Wim, Corcia Philippe, Chiò Adriano, Shaw Pamela J, Morrison Karen E, Veldink Jan H, van den Berg Leonard H, Shaw Christopher E, Powell John F, Silani Vincenzo, Hardy John A, Houlden Henry, Owen Michael J, Turner Martin R, Ryten Mina, Al-Chalabi Ammar 15 Mar 2023, In: Neurobiology of Disease. 180 8 p.

Effects of enzyme replacement therapy on cardiac function in classic infantile Pompe disease

Scheffers L E, Kok R, van den Berg L E, Jmp Hout, Boersma E, van Capelle C I, Helbing W A, Ploeg A T, Koopman L P 7 Mar 2023, In: International Journal of Cardiology. 380 , p. 65-71 7 p.

Association Between Serum Lipids and Survival in Patients With Amyotrophic Lateral Sclerosis:A Meta-analysis and Population-Based Study

Janse Van Mantgem Mark R., Van Rheenen Wouter, Hackeng Anemone V., Van Es Michael A., Veldink Jan H., Van Den Berg Leonard H., Van Eijk Ruben P.A. 7 Mar 2023, In: Neurology. 100 , p. E1062-E1071

Large-scale analyses of CAV1 and CAV2 suggest their expression is higher in post-mortem ALS brain tissue and affects survival

Adey Brett N, Cooper-Knock Johnathan, Al Khleifat Ahmad, Fogh Isabella, van Damme Philip, Corcia Philippe, Couratier Philippe, Hardiman Orla, McLaughlin Russell, Gotkine Marc, Drory Vivian, Silani Vincenzo, Ticozzi Nicola, Veldink Jan H, van den Berg Leonard H, de Carvalho Mamede, Pinto Susana, Mora Pardina Jesus S, Povedano Panades Mónica, Andersen Peter M, Weber Markus, Başak Nazli A, Shaw Christopher E, Shaw Pamela J, Morrison Karen E, Landers John E, Glass Jonathan D, Vourc'h Patrick, Dobson Richard J B, Breen Gerome, Al-Chalabi Ammar, Jones Ashley R, Iacoangeli Alfredo Mar 2023, In: Frontiers in Cellular Neuroscience. 17 12 p.

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