prof. dr. J.H.H.M. (Janneke) van de Wijgert

prof. dr. J.H.H.M. (Janneke) van de Wijgert

Full Professor
prof. dr. J.H.H.M. (Janneke) van de Wijgert
  • Julius Center, dept. Epidemiology & Health Economics

Research Programs

Infection & Immunity



Prof. Janneke van de Wijgert, MD PhD MPH, is a translational infectious disease researcher, educated in biomedical sciences and medicine (Utrecht University, Netherlands), and public health epidemiology (University of California at Berkeley, USA). Her work experience includes clinical epidemiological and public health research, laboratory research, and product development in various European, African, Asian, and American countries. Former employers include the University of California at San Francisco (5 years of which as Director of the UZ-UCSF Collaborative HIV Research Program in Harare, Zimbabwe), the Population Council in New York, the Amsterdam University Medical Center, and the University of Liverpool, UK. She was appointed Full Professor in the Julius Center for Health Sciences and Primary Care of the University Medical Center (UMC) Utrecht in 2017, and as Chief Science Officer at the Dutch Institute of Public Health and the Environment (RIVM) in 2022. She currently divides her time between the UMC Utrecht and the RIVM. She has supervised/is supervising multiple PhD, Master’s and Bachelor students, and has published more than 200 peer-reviewed papers. 
Janneke van de Wijgert’s main areas of research and teaching include 1) general infectious and immune-mediated disease epidemiology (including COVID-19); 2) the role of the human microbiome in health and disease; 3) the role of the cervicovaginal microbiome in reproductive and neonatal health and disease, and in prevention of HIV transmission; and 4) evaluation of diagnostics, treatments, and prevention interventions in these areas. In addition to traditional epidemiological approaches, she has specialised in incorporating ‘-omics’ and other complex biological data into epidemiological models. During the COVID-19 epidemic, she has worked with eHealth applications to control epidemic spread.

A complete list of publications can be found on ORCID:



Side Activities

Chief Science Officer, Dutch Institute of Public Health and the Environment (RIVM; as of 1 March 2022).

Member of the "Begeleidingscommissie Digitale Ondersteuning Bestrijding Covid-19" of the Dutch Ministry of Health and Sports (May 2020-Feb 2022).

Regular peer reviewer for journals and funding agencies (ongoing).

Regular invited speaker, session chair, or Scientific Advisory Committee member at scientific meetings and conferences (ongoing).

Unpaid advisor of biotech companies in infectious disease diagnostics and therapeutics (ongoing).

Research Output (104)

Genital tract infections, the vaginal microbiome and gestational age at birth among pregnant women in South Africa:a cohort study protocol

Gigi Ranjana M S, Mdingi Mandisa M, Jung Hyunsul, Claassen-Weitz Shantelle, Bütikofer Lukas, Klausner Jeffrey D, Muzny Christina A, Taylor Christopher M, van de Wijgert Janneke H H M, Peters Remco P H, Low Nicola 28 Dec 2023, In: BMJ Open. 13 , p. 1-8 8 p.

The impact of Bacillus Calmette-Guérin vaccination on antibody response after COVID-19 vaccination

Taks Esther J M, Moorlag Simone J C F M, Föhse Konstantin, Simonetti Elles, van der Gaast-de Jongh Christa E, van Werkhoven Cornelis H, Bonten Marc J M, Oever Jaap Ten, de Jonge Marien I, van de Wijgert Janneke H H M, Netea Mihai G 17 Nov 2023, In: iScience. 26 12 p.

Vaccine effectiveness of primary and booster COVID-19 vaccinations against SARS-CoV-2 infection in the Netherlands from July 12, 2021 to June 6, 2022:A prospective cohort study

Huiberts Anne J, de Gier Brechje, Hoeve Christina E, de Melker Hester E, Hahné Susan J M, den Hartog Gerco, Grobbee Diederick E, van de Wijgert Janneke H H M, van den Hof Susan, Knol Mirjam J 20 Apr 2023, In: International Journal of Infectious Diseases. 133 , p. 36-42 7 p.

BCG Vaccination of Health Care Workers Does Not Reduce SARS-CoV-2 Infections nor Infection Severity or Duration:a Randomized Placebo-Controlled Trial

Claus Juana, Ten Doesschate Thijs, Gumbs Cheyenne, van Werkhoven Cornelis H, van der Vaart Thomas W, Janssen Axel B, Smits Gaby, van Binnendijk Rob, van der Klis Fiona, van Baarle Debbie, Paganelli Fernanda L, Leavis Helen, Verhagen Lilly M, Joosten Simone A, Bonten Marc J M, Netea Mihai G, van de Wijgert Janneke H H M, 28 Mar 2023, In: mBio. 14 16 p.

Vulvovaginal yeast infections during pregnancy and perinatal outcomes:systematic review and meta-analysis

Gigi Ranjana M S, Buitrago-Garcia Diana, Taghavi Katayoun, Dunaiski Cara-Mia, van de Wijgert Janneke H H M, Peters Remco P H, Low Nicola 21 Mar 2023, In: BMC Women's Health. 23

The endometrial microbiota of women with or without a live birth within 12 months after a first failed IVF/ICSI cycle

Bui Bich Ngoc, van Hoogenhuijze Nienke, Viveen Marco, Mol Femke, Teklenburg Gijs, de Bruin Jan Peter, Besselink Dagmar, Brentjens Linda Stevens, Mackens Shari, Rogers Malbert R.C., Steba Gaby S., Broekmans Frank, Paganelli Fernanda L., van de Wijgert Janneke H.H.M. 1 Mar 2023, In: Scientific Reports. 13 , p. 1-11

Nitrofurantoin failure in males with an uncomplicated urinary tract infection:a primary care observational cohort study

Platteel Tamara N., Beets Marijn T., Teeuwissen Hendrik A., Doesschate Thijs Ten, van de Wijgert Janneke Hhm, Venekamp Roderick P., van de Pol Alma C. 1 Mar 2023, In: The British journal of general practice : the journal of the Royal College of General Practitioners. 73 , p. e204-e210

Effectiveness of bivalent mRNA booster vaccination against SARS-CoV-2 Omicron infection, the Netherlands, September to December 2022

Huiberts Anne J, de Gier Brechje, Hoeve Christina E, de Melker Hester E, Hahné Susan Jm, center Radboud, van de Wijgert Janneke Hhm, van den Hof Susan, Knol Mirjam J 16 Feb 2023, In: Eurosurveillance. 28

Urine and vaginal microbiota compositions of postmenopausal and premenopausal women differ regardless of recurrent urinary tract infection and renal transplant status

Hugenholtz Floor, van der Veer Charlotte, Terpstra Matty L, Borgdorff Hanneke, van Houdt Robin, Bruisten Sylvia, Geerlings Suzanne E, van de Wijgert Janneke H H M Dec 2022, In: Scientific Reports. 12

Diagnostic accuracy of SARS-CoV-2 rapid antigen self-tests in asymptomatic individuals in the Omicron period:a cross-sectional study

Venekamp Roderick P, Schuit Ewoud, Hooft Lotty, Veldhuijzen Irene K, van den Bijllaardt Wouter, Pas Suzan D, Zwart Vivian F, Lodder Esther B, Hellwich Marloes, Koppelman Marco, Molenkamp Richard, Wijers Constantijn Jh, Vroom Irene H, Smeets Leonard C, Nagel-Imming Carla R S, Han Wanda G H, van den Hof Susan, Kluytmans Jan AJW, van de Wijgert Janneke H M, Moons Karel G M 12 Nov 2022, In: Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases. 29 , p. 391.e1-391.e7 7 p.

All research output

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