dr. S. (Stefano) Mandija

dr. S. (Stefano) Mandija

Assistant Professor
dr. S. (Stefano) Mandija
  • Computational Imaging

Research Programs

Strategic Program Cancer



Stefano is currently employed as assistant professor at the radiotherapy department of the University Medical Center Utrecht (The Netherlands). His research topics range from fundamental and methodological research to clinical development of quantitative MRI methods and MRI biomarkers for diagnostic and radiotherapy treatment response prediction and monitoring. In particular, he works on the characterization of tissue electrical properties for radiotherapy treatments efficacy assessment using MRI (NWO recipient VENI grant 2020), MRI-guided cardiac radio-ablation using stereotactic radiotherapy ( consortium), MRI-based guidance of spinal cord stimulation (RESTORE and Prep2GO consortia), and he also supports the development and translation of quantitative MRI methods in clinical settings (MR-STAT).


Stefano was born in Camposampiero, Padua (Italy) in September 1988. He was educated as a bioengineer at the University of Padua, 2007-2013. Afterwards, he moved to The Netherlands where he received his Ph.D. in the field of non-invasive characterization of tissue electrical properties with MRI at the University Medical Center Utrecht (The Netherlands) in 2018. Subsequently, he was offered a Post-Doc position at the Radiology and Radiotherapy departments of the University Medical Center Utrecht. Because of his passion for MRI and his positive attitude, which makes him looking at research challenges as new opportunities to expand his knowledge and to establish new collaborations, he also recently started investigating MRI-based guidance of cardiac ablation using stereotactic radiotherapy at the radiotherapy department of the University Medical Center Utrecht within the European STOPSTORM consortium.

Fellowship and Awards

NWO VENI Grant (2020): MR-based measurements of ‘Tissue ElectroMagnetic Properties in radiation Oncology (TEMPO)’: A predictive tool for early-stage assessment of radiotherapy treatments

Junior Fellow of the International Society for Magnetic Resonance in Medicine, ISMRM (2020)

Trainee Educational Stipend of the International Society for Magnetic Resonance in Medicine, ISMRM (2014, 2015, 2016)

Research Output (41)

Synthetic MRI with Magnetic Resonance Spin TomogrAphy in Time-Domain (MR-STAT):Results from a Prospective Cross-Sectional Clinical Trial

Kleinloog Jordi P D, Mandija Stefano, D'Agata Federico, Liu Hongyan, van der Heide Oscar, Koktas Beyza, Dankbaar Jan Willem, Keil Vera C, Vonken Evert-Jan, Jacobs Sarah M, van den Berg Cornelis A T, Hendrikse Jeroen, van der Kolk Anja G, Sbrizzi Alessandro May 2023, In: Journal of Magnetic Resonance Imaging. 57 , p. 1451-1461 11 p.

STereotactic Arrhythmia Radioablation (STAR):the Standardized Treatment and Outcome Platform for Stereotactic Therapy Of Re-entrant tachycardia by a Multidisciplinary consortium ( and review of current patterns of STAR practice in Europe

Grehn Melanie, Mandija Stefano, Miszczyk Marcin, Krug David, Tomasik Bartłomiej, Stickney Kristine E, Alcantara Pino, Alongi Filippo, Anselmino Matteo, Aranda Ricardo Salgado, Balgobind Brian V, Boda-Heggemann Judit, Boldt Leif-Hendrik, Bottoni Nicola, Cvek Jakub, Elicin Olgun, De Ferrari Gaetano Maria, Hassink Rutger J, Hazelaar Colien, Hindricks Gerhard, Hurkmans Coen, Iotti Cinzia, Jadczyk Tomasz, Jiravsky Otakar, Jumeau Raphaël, Buus Kristiansen Steen, Levis Mario, López Manuel Algara, Martí-Almor Julio, Mehrhof Felix, Møller Ditte Sloth, Molon Giulio, Ouss Alexandre, Peichl Petr, Plasek Jiri, Postema Pieter G, Quesada Aurelio, Reichlin Tobias, Rordorf Roberto, Rudic Boris, Saguner Ardan M, Ter Bekke Rachel M A, Torrecilla José López, Troost Esther G C, Vitolo Viviana, Andratschke Nicolaus, Zeppenfeld Katja, Blamek Slawomir, Fast Martin, de Panfilis Ludovica, Blanck Oliver, Pruvot Etienne, Verhoeff Joost J C 6 Mar 2023, In: Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology. 25 , p. 1284-1295 12 p.

Walking with the ISMRM in the footprints of our MR history

Mandija Stefano, Ma Chao, Bai Ruiliang, Feng Li, Giganti Francesco, Ianus Andrada, Lee Hong-Hsi, Li Fei, Welton Thomas, Calamante Fernando Mar 2023, In: Magnetic Resonance in Medicine. 89 , p. 883-885 3 p.

Acceleration Strategies for MR-STAT: Achieving High-Resolution Reconstructions on a Desktop PC Within 3 Minutes

Liu Hongyan, van der Heide Oscar, Mandija Stefano, van den Berg Cornelis A. T., Sbrizzi Alessandro Oct 2022, In: IEEE transactions on medical imaging. 41 , p. 2681-2692 12 p.

Intrafraction motion during radiotherapy of breast tumor, breast tumor bed, and individual axillary lymph nodes on cine magnetic resonance imaging

Groot Koerkamp Maureen L, van den Bongard H J G Desirée, Philippens Marielle E P, van der Leij Femke, Mandija Stefano, Houweling Antonetta C Jul 2022, In: Physics and Imaging in Radiation Oncology. 23 , p. 74-79 6 p.

Dynamic Contrast-enhanced and Diffusion-weighted Magnetic Resonance Imaging for Response Evaluation After Single-Dose Ablative Neoadjuvant Partial Breast Irradiation

Vasmel Jeanine E., Groot Koerkamp Maureen L., Mandija Stefano, Veldhuis Wouter B., Moman Maaike R., Froeling Martijn, van der Velden Bas H.M., Charaghvandi Ramona K., Vreuls Celien P.H., van Diest Paul J., van Leeuwen A. M.Gijs, van Gorp Joost, Philippens Marielle E.P., van Asselen Bram, Lagendijk Jan J.W., Verkooijen Helena M., van den Bongard H. J.G.Desirée, Houweling Antonetta C. 8 Apr 2022, In: Advances in Radiation Oncology. 7 , p. 1-11

First experimental exploration of real-time cardiorespiratory motion management for future stereotactic arrhythmia radioablation treatments on the MR-linac

Akdag Osman, Borman Pim T S, Woodhead Peter L, Uijtewaal Prescilla, Mandija Stefano, van Asselen Bram, Verhoeff Joost J C, Raaymakers Bas W, Fast Martin F 21 Feb 2022, In: Physics in medicine and biology. 67 , p. 1-14

Feasibility of cardiac-synchronized quantitative T1 and T2 mapping on a hybrid 1.5 Tesla magnetic resonance imaging and linear accelerator system

Akdag Osman, Mandija Stefano, van Lier Astrid L H M W, Borman PTS, Schakel Tim, Alberts Eveline, van der Heide Oscar, Hassink Rutger J, Verhoeff Joost J C, Mohamed Hoesein Firdaus A A, Raaymakers Bas W, Fast Martin F Jan 2022, In: Physics and Imaging in Radiation Oncology. 21 , p. 153-159 7 p.

Application of Supervised Descent Method to MRI Electrical Properties Tomography

Zumbo Sabrina, Mandija Stefano, Meliado Flavio, Van Den Berg Cornelis A.T., Isernia Tommaso, Bevacqua Martina T. 2022,

Advances in MRI based Electrical Properties Tomography:a Comparison between Physics-supported Learning Approaches

Zumbo Sabrina, Mandija Stefano, Meliado Ettore Flavio, Stijnman Peter, Meerbothe Thierry, Van Den Berg Cornelis A.T., Isernia Tommaso, Bevacqua Martina T. 2022,

All research output

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