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dr. C.A. (Caroline) Lindemans

dr. C.A. (Caroline) Lindemans

Assistant Professor - medical
dr. C.A. (Caroline) Lindemans
  • SCT patient care

Biography

Biography

Caroline Lindemans, MD, PhD is a pediatrician, BMT specialist  and pediatric immunologist in the UMC Utrecht. Appointed as a consultant in HCT she has a special  research interest in graft versus host disease, intestinal toxicity, it’s prevention and therapy.  After receiving a KWF fellowship grant she recently worked at Memorial Sloan Kettering Cancer Center in the Research groups of Marcel van den Brink  and Alan Hanash resulting in a first author Nature paper, published December 2015. She has ongoing collaborations with these groups and is currently expanding this line of research in the UMC Utrecht.  Caroline is an active member of various international working committees (e.g. EBMT, CIBMTR: chair of one of the CIBMTR working committees).

Side Activities

  • Co-chair CIBMTR working committee Infection and Immunity February 2014—Feb 2017
  • Medical Consultant Chimerix europe (Brincidofovir studies): 2015-heden

Fellowship and Awards

  • 2000 Wilhelmina Children's Hospital Student Research Prize
  • 2010 ASBMT Travel grant for young investigators $500
  • 2012 Abstract award winner international cord blood symposium
  • 2012 UMC Utrecht mobilization grant  €20.000 euro
  • 2013 Wilhelmina Children’s hospital Fund: Leading ladies  research stimulation grant €125.000 euro
  • 2013 Travel Stipendium Nijbakker Morra Foundation €9.600 euro
  • 2013 KWF (Dutch Cancer Society) Clinical fellowship Grant €250.000 euro. To study tissue regeneratation in GVHD.
  • 2014 ASH Abstract Achievement Award

Research Output (93)

Modified Delphi procedure-based expert consensus on endpoints for an international disease registry for Metachromatic Leukodystrophy:The European Metachromatic Leukodystrophy initiative (MLDi)

Schoenmakers Daphne H., Beerepoot Shanice, van den Berg Sibren, Adang Laura, Bley Annette, Boelens Jaap Jan, Fumagalli Francesca, Goettsch Wim G., Grønborg Sabine, Groeschel Samuel, van Hasselt Peter M., Hollak Carla E.M., Lindemans Caroline, Mochel Fanny, Mol Peter G.M., Sevin Caroline, Zerem Ayelet, Schöls Ludger, Wolf Nicole I. 14 Feb 2022, In: Orphanet Journal of Rare Diseases. 17 , p. 48

Lymphoid and myeloid immune cell reconstitution after nicotinamide-expanded cord blood transplantation

de Koning Coco, Tao Weiyang, Lacna Amelia, van Veghel Karin, Horwitz Mitchell E., Sanz Guillermo, Jagasia Madan H., Wagner John E., Stiff Patrick J., Hanna Rabi, Cilloni Daniela, Valcárcel David, Peled Tony, Galamidi Cohen Einat, Goshen Uri, Pandit Aridaman, Lindemans Caroline A., Jan Boelens Jaap, Nierkens Stefan Nov 2021, In: Bone Marrow Transplantation. 56 , p. 2826-2833 8 p.

KIR3DS1 directs NK cell-mediated protection against human adenovirus infections

Jung Johannes M, Ching Wilhelm, Baumdick Martin E, Hofmann-Sieber Helga, Bosse Jens B, Koyro Tobias, Möller Kimberly J, Wegner Lucy, Niehrs Annika, Russu Kristina, Ohms Mareike, Zhang Wenli, Ehrhardt Anja, Duisters Kevin, Spierings Eric, Hölzemer Angelique, Körner Christian, Jansen Suze A, Peine Sven, Königs Ingo, Lütgehetmann Marc, Perez Daniel, Reinshagen Konrad, Lindemans Caroline A, Altfeld Marcus, Belderbos Mirjam, Dobner Thomas, Bunders Madeleine J 17 Sep 2021, In: Science Immunology. 6 , p. 1-13 14 p.

Allogenic Hematopoietic Stem Cell Transplantation Is Feasible in Pediatric Patients with an Active or Recently Diagnosed Invasive Fungal Infection

Rotte Laura G.Y., Loeffen Yvette G.T., Bierings Marc B., Wolfs Tom F.W., Lindemans Caroline A. Sep 2021, In: Transplantation and Cellular Therapy. 27 , p. 781.e1-781.e5

Long-term effect of hematopoietic cell transplantation on systemic inflammation in patients with mucopolysaccharidoses

van den Broek Brigitte T A, Lindemans Caroline A, Boelens Jaap Jan, Delemarre Eveline M, Drylewicz Julia, Verhoeven-Duif Nanda, van Hasselt Peter M, Nierkens Stefan 24 Aug 2021, In: Blood Advances. 5 , p. 3092-3101 10 p.

Hematopoietic dysfunction during graft-versus-host disease:A self-destructive process?

Müskens Konradin F., Lindemans Caroline A., Belderbos Mirjam E. 10 Aug 2021, In: Cells. 10 , p. 1-17

A Minimal Parameter Set Facilitating Early Decision-making in the Diagnosis of Hemophagocytic Lymphohistiocytosis

Smits Bas M, van Montfrans Joris, Merrill Samuel A, van de Corput Lisette, van Gijn Mariëlle, de Vries Andrica, van den Bos Cor, Abbink Floor, van der Molen Renate G, Dors Natasja, Lindemans Caroline, Boelens Jaap J, Nierkens Stefan 29 Mar 2021, In: Journal of Clinical Immunology. 41 , p. 1219-1228 10 p.

The pulmonary metatranscriptome prior to pediatric HCT identifies post-HCT lung injury

Zinter Matt S., Lindemans Caroline A., Versluys Birgitta A., Mayday Madeline Y., Sunshine Sara, Reyes Gustavo, Sirota Marina, Sapru Anil, Matthay Michael A., Kharbanda Sandhya, Dvorak Christopher C., Boelens Jaap J., DeRisi Joseph L. 25 Mar 2021, In: Blood. 137 , p. 1679-1689 11 p.

New insights in phenotype and treatment of lung disease immuno-deficiency and chromosome breakage syndrome (LICS)

Willemse Brigitte W M, van der Crabben Saskia N, Kerstjens-Frederikse Wilhelmina S, Timens Wim, van Montfrans Joris M, Lindemans Caroline A, Boelens Jaap Jan, Hennus Marije P, van Haaften Gijs 19 Mar 2021, In: Orphanet Journal of Rare Diseases. 16

CD4+ T-cell reconstitution predicts survival outcomes after acute graft-versus-host-disease:a dual-center validation

de Koning Coco, Prockop Susan, van Roessel Ichelle, Kernan Nancy, Klein Elizabeth, Langenhorst Jurgen, Szanto Celina, Belderbos Mirjam, Bierings Marc, Boulad Farid, Bresters Dorine, Cancio Maria, Curran Kevin, Kollen Wouter, O'Reilly Richard, Scaradavou Andromachi, Spitzer Barbara, Versluijs Birgitta, Huitema Alwin, Lindemans Caroline, Nierkens Stefan, Boelens Jaap Jan 11 Feb 2021, In: Blood. 137 , p. 848-855 8 p.

All research output

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