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dr. dr.h.c.mult A.L.G. (Alexander) Leemans

dr. dr.h.c.mult A.L.G. (Alexander) Leemans

Associate Professor
dr. dr.h.c.mult A.L.G. (Alexander) Leemans
  • Image Sciences Institute

Research Programs

Biography

Biography

Alexander Leemans is a physicist who received his Ph.D. in 2006 at the University of Antwerp, Belgium. From 2007 to 2009, he worked as a postdoctoral researcher at the Cardiff University Brain Research Imaging Center (CUBRIC), Cardiff University, Wales, United Kingdom. In 2009, he joined the Image Sciences Institute (ISI), University Medical Center Utrecht, the Netherlands, where he currently holds a tenured faculty position as Associate Professor. His current research interests include modeling, processing, visualizing and analyzing diffusion MRI data for investigating microstructural and architectural tissue organization. He heads the PROVIDI Lab and is the developer of ExploreDTI, which is a graphical toolbox for investigating diffusion MRI data.

Research line

Diffusion MRI

Most recent key publications

1: C. Lebel, L. Walker, A. Leemans, L. Phillips, C. Beaulieu, "Microstructural Maturation of the Human Brain from Childhood to Adulthood", NeuroImage, 2008, nr. 3, vol. 40, pp. 1044-1055
2: A. Leemans, D.K. Jones, "The B-matrix must be rotated when correcting for subject motion in DTI data", Magnetic Resonance in Medicine, 2009, nr. 1, vol. 62, pp. 1336-1349
3: J.D. Tournier, S. Mori, A. Leemans, "Diffusion tensor imaging and beyond", Magnetic Resonance in Medicine, 2011, nr. 6, vol. 65, pp. 1532-1556
4: B. Jeurissen, A. Leemans, J.D. Tournier, D.K. Jones, J. Sijbers, "Investigating the prevalence of complex fiber configurations in white matter tissue with diffusion MRI", Human Brain Mapping, 2013, nr. 11, vol. 34, pp. 2747-2766
5: S.B. Vos, D.K. Jones, M.A. Viergever, A. Leemans, "Partial volume effect as a hidden covariate in DTI analyses", NeuroImage, 2011, nr. 4, vol. 55, pp. 1566-1576

Fellowship and Awards

VIDI (NWO)

FC-EW (NWO)

USERN (UNESCO)

PhD fellowship (IWT)

Honorary Doctorate (Chubut)

Honorary Doctorate (Kharkiv)

Young Investigator Award (BHPA)

Outstanding Teacher Award (ISMRM)

Research Output (247)

Association of Superficial White Matter Alterations with Cerebrospinal Fluid Biomarkers and Cognitive Decline in Neurodegenerative Dementia

Contarino Valeria Elisa, Siggillino Silvia, Arighi Andrea, Scola Elisa, Fumagalli Giorgio Giulio, Conte Giorgio, Rotondo Emanuela, Galimberti Daniela, Pietroboni Anna Margherita, Carandini Tiziana, Leemans Alexander, Bianchi Anna Maria, Triulzi Fabio Maria 2022, In: Journal of Alzheimer's Disease. 85 , p. 431-442 12 p.

Tracking the Corticospinal Tract in Patients With High-Grade Glioma:Clinical Evaluation of Multi-Level Fiber Tracking and Comparison to Conventional Deterministic Approaches

Zhylka Andrey, Sollmann Nico, Kofler Florian, Radwan Ahmed, De Luca Alberto, Gempt Jens, Wiestler Benedikt, Menze Bjoern, Krieg Sandro M., Zimmer Claus, Kirschke Jan S., Sunaert Stefan, Leemans Alexander, Pluim Josien P.W. 14 Dec 2021, In: Frontiers in oncology. 11 , p. 1-15

Indices of callosal axonal density and radius from diffusion MRI relate to upper and lower limb motor performance

Gooijers J., De Luca A., Zivari Adab H., Leemans A., Roebroeck A., Swinnen S. P. 1 Nov 2021, In: NeuroImage. 241 , p. 1-12

Tractography dissection variability:What happens when 42 groups dissect 14 white matter bundles on the same dataset?

Schilling Kurt G., Rheault François, Petit Laurent, Hansen Colin B., Nath Vishwesh, Yeh Fang Cheng, Girard Gabriel, Barakovic Muhamed, Rafael-Patino Jonathan, Yu Thomas, Fischi-Gomez Elda, Pizzolato Marco, Ocampo-Pineda Mario, Schiavi Simona, Canales-Rodríguez Erick J., Daducci Alessandro, Granziera Cristina, Innocenti Giorgio, Thiran Jean Philippe, Mancini Laura, Wastling Stephen, Cocozza Sirio, Petracca Maria, Pontillo Giuseppe, Mancini Matteo, Vos Sjoerd B., Vakharia Vejay N., Duncan John S., Melero Helena, Manzanedo Lidia, Sanz-Morales Emilio, Peña-Melián Ángel, Calamante Fernando, Attyé Arnaud, Cabeen Ryan P., Korobova Laura, Toga Arthur W., Vijayakumari Anupa Ambili, Parker Drew, Verma Ragini, Radwan Ahmed, Sunaert Stefan, Emsell Louise, De Luca Alberto, Leemans Alexander, Bajada Claude J., Haroon Hamied, Tax Chantal M.W., Fernandes Francisco Guerreiro, Raemaekers Mathijs, Nov 2021, In: NeuroImage. 243 , p. 1-18

COVID-19 vaccine boosters:The good, the bad, and the ugly

Rzymski Piotr, Camargo Carlos A., Fal Andrzej, Flisiak Robert, Gwenzi Willis, Kelishadi Roya, Leemans Alexander, Nieto Juan J., Ozen Ahmet, Perc Matjaž, Poniedziałek Barbara, Sedikides Constantine, Sellke Frank, Skirmuntt Emilia C., Stashchak Anzhela, Rezaei Nima Nov 2021, In: Vaccines. 9

Diffusion kurtosis imaging of white matter in bipolar disorder

Goghari Vina M, Kusi Mavis, Shakeel Mohammed K, Beasley Clare, David Szabolcs, Leemans Alexander, De Luca Alberto, Emsell Louise 31 Jul 2021, In: Psychiatry Research - Neuroimaging. 317 , p. 1-9

On the generalizability of diffusion MRI signal representations across acquisition parameters, sequences and tissue types:Chronicles of the MEMENTO challenge

De Luca Alberto, Ianus Andrada, Leemans Alexander, Palombo Marco, Shemesh Noam, Zhang Hui, Alexander Daniel C, Nilsson Markus, Froeling Martijn, Biessels Geert-Jan, Zucchelli Mauro, Frigo Matteo, Albay Enes, Sedlar Sara, Alimi Abib, Deslauriers-Gauthier Samuel, Deriche Rachid, Fick Rutger, Afzali Maryam, Pieciak Tomasz, Bogusz Fabian, Aja-Fernández Santiago, Özarslan Evren, Jones Derek K, Chen Haoze, Jin Mingwu, Zhang Zhijie, Wang Fengxiang, Nath Vishwesh, Parvathaneni Prasanna, Morez Jan, Sijbers Jan, Jeurissen Ben, Fadnavis Shreyas, Endres Stefan, Rokem Ariel, Garyfallidis Eleftherios, Sanchez Irina, Prchkovska Vesna, Rodrigues Paulo, Landman Bennet A, Schilling Kurt G 6 Jul 2021, In: NeuroImage. 240 17 p.

White matter microstructure of the neural emotion regulation circuitry in mild traumatic brain injury

van der Horn Harm Jan, Mangina Namrata R., Rakers Sandra E., Kok Jelmer G., Timmerman Marieke E., Leemans Alexander, Spikman Jacoba M., van der Naalt Joukje May 2021, In: European Journal of Neuroscience. 53 , p. 3463-3475 13 p.

Diffusion MRI harmonization enables joint-analysis of multicentre data of patients with cerebral small vessel disease

de Brito Robalo Bruno M., Biessels Geert Jan, Chen Christopher, Dewenter Anna, Duering Marco, Hilal Saima, Koek Huiberdina L., Kopczak Anna, Yin Ka Lam Bonnie, Leemans Alexander, Mok Vincent, Onkenhout Laurien P., van den Brink Hilde, de Luca Alberto Jan 2021, In: NeuroImage: Clinical. 32 , p. 1-14

Iranian Brain Imaging Database:A Neuropsychiatric Database of Healthy Brain

Batouli Seyed Amir Hossein, Sisakhti Minoo, Haghshenas Shirin, Dehghani Hamed, Sachdev Perminder, Ekhtiari Hamed, Kochan Nicole, Wen Wei, Leemans Alexander, Kohanpour Mohsen, Oghabian Mohammad Ali Jan 2021, In: Basic and clinical neuroscience. 12 , p. 115-132 18 p.

All research output

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