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prof. dr. R.H.J. Houwen MSc

prof. dr. R.H.J. Houwen MSc

Professor Emeritus
prof. dr. R.H.J. Houwen MSc
  • Gastroenterology & Hepatology patient care

Biography

Biography

Professor Houwen is kinderarts-MDL sinds 1988 en beoefent het vak in de volle breedte, waarbij er met name interesse is voor leverziekten en genetisch bepaalde aandoeningen van de tractus digestivus.

Wetenschappelijk onderzoek: Ophelderen pathofysiologie van genetisch bepaalde ziekten lever en tractus digestivus en het ontwikkelen van behandelmethoden hiervoor.

  • Studie geneeskunde, Erasmus Universiteit Rotterdam
  • Opleiding tot kinderarts,  Sophia Kinderziekenhuis Rotterdam
  • Opleiding tot  kinderarts-MDL, afdeling kindergeneeskunde en kinder-MDL, UMCG
  • Research and clinical fellow, Hospital for Sick Children Toronto
  • Staflid afdeling kinder-MDL, UMCU/WKZ
  • Hoogleraar Pediatric Gastroenterology

 

Side Activities

Lid van de Medische Adviesraad van:

  • Nederlandse Coeliakie Vereniging

 Wetenschappelijke verenigingen:

  • Sectie Kinder-MDL van de Nederlandse Vereniging voor Kindergeneeskunde (S-MDL)
  • Nederlandse Vereniging voor Hepatologie (NVH)
  • Nederlandse Vereniging voor Gastro-enterologie (NVGE)
  • European Society for Pediatric Gastroenterology, Hepatology and Nutrition (ESPGHAN)
  • European Association for the Study of Liver Diseases (EASL)
  • American Association for the Study of Liver Diseases (AASLD)
  • American Gastroenterological Association (AGA)

Research Output (287)

A Potential Treatment of Congenital Sodium Diarrhea in Patients With Activating GUCY2C Mutations

van Vugt Anke H M, Bijvelds Marcel J C, de Jonge Hugo R, Meijsen Kelly F, Restin Tanja, Bryant Manuel B, Ballauff Antje, Koot Bart, Müller Thomas, Houwen Roderick H J, Janecke Andreas R, Middendorp Sabine 18 Nov 2021, In: Clinical and translational gastroenterology. 12 , p. 1-4

Erratum: DGAT2 partially compensates for lipid-induced ER stress in human DGAT1-deficient intestinal stem cells

van Rijn Jorik M, van Hoesel Marliek, de Heus Cecilia, van Vugt Anke H M, Klumperman Judith, Nieuwenhuis Edward E S, Houwen Roderick H J, Middendorp Sabine 6 Oct 2021, In: Journal of Lipid Research. 62 , p. 1-1

Relationships between changes in autotaxin, pruritus, and serum bile acids after odevixibat treatment in patients with progressive familial intrahepatic cholestasis: data from a pooled analysis.

Gonzales Emmanuel, Thompson Richard J, Kamath Binita M., Lacaille Florence, Lainka Elke, Shteyer Eyal, D'Antiga Lorenzo, Houwen RHJ, Verkade Henkjan J., Durmaz Özlem, Grammatikopoulos Tassos, Loomes Kathleen M., Karpen Saul J., Mack Cara Lynn, Ni Quinhong, Kjems Lise, Horn Patrick Oct 2021, In: Hepatology. 74 , p. 30A-31A 2 p.

Novel Orally Formulated Mixed Micelles Optimize Vitamin K Absorption Under Bile-Deficient Conditions

Rooimans Thijs, Minderhoud Tanca, Leal Nerea, Vromans Herman, van Nostrum Cornelus, van Hasselt Peter, Rodriguez M., Sun F., Oussoren C., Slot T. K., van der Ham M., Janssens G. E.P.J., de Sain-van der Velden M. G.M., Houwen R. H.J., de Koning T. J., Hennink W. E., Sep 2021, In: Gastroenterology. 161 , p. 1056-1059.e5

Substantial clinical benefits with odevixibat treatment across progressive familial intrahepatic cholestasis genetic deficiencies: subgroup analysis of serum bile acids, pruritus, and safety using pooled data from the PEDFIC 1 and 2 studies

Thompson Richard, Horn Patrick, Houwen Roderick H. J., Lacaille Florence, Ni Quanhong, Stein Philip, Tessier Mary Elizabeth, Thompson Carrie, Vittorio Jennifer, Kjems Lise Jul 2021, In: Journal of Hepatology. 75 , p. S684-S685

Direct Measurement of ATP7B Peptides Is Highly Effective in the Diagnosis of Wilson Disease

Collins Christopher J., Yi Fan, Dayuha Remwilyn, Duong Phi, Horslen Simon, Camarata Michelle, Coskun Ayse K., Houwen Roderick H.J., Pop Tudor L., Zoller Heinz, Yoo Han wook, Jung Sung Won, Weiss Karl H., Schilsky Michael L., Ferenci Peter, Hahn Si Houn Jun 2021, In: Gastroenterology. 160 , p. 2367-2382.e1

Liver Steatosis and Diarrhea After Liver Transplantation for Progressive Familial Intrahepatic Cholestasis Type 1:Can Biliary Diversion Solve These Problems?

Knisely A S, Houwen Roderick H J 1 Mar 2021, In: Journal of Pediatric Gastroenterology and Nutrition. 72 , p. 341-342 2 p.

Broadly effective metabolic and immune recovery with C5 inhibition in CHAPLE disease

Ozen Ahmet, Kasap Nurhan, Vujkovic-Cvijin Ivan, Apps Richard, Cheung Foo, Karakoc-Aydiner Elif, Akkelle Bilge, Sari Sinan, Tutar Engin, Ozcay Figen, Uygun Dilara Kocacik, Islek Ali, Akgun Gamze, Selcuk Merve, Sezer Oya Balci, Zhang Yu, Kutluk Gunsel, Topal Erdem, Sayar Ersin, Celikel Cigdem, Houwen Roderick H J, Bingol Aysen, Ogulur Ismail, Eltan Sevgi Bilgic, Snow Andrew L, Lake Camille, Fantoni Giovanna, Alba Camille, Sellers Brian, Chauvin Samuel D, Dalgard Clifton L, Harari Olivier, Ni Yan G, Wang Ming-Dauh, Devalaraja-Narashimha Kishor, Subramanian Poorani, Ergelen Rabia, Artan Reha, Guner Sukru Nail, Dalgic Buket, Tsang John, Belkaid Yasmine, Ertem Deniz, Baris Safa, Lenardo Michael J 4 Jan 2021, In: Nature immunology. 22 , p. 128-139 12 p.

Enhanced Collagen Deposition in the Duodenum of Patients with Hyaline Fibromatosis Syndrome and Protein Losing Enteropathy

van Rijn Jorik M, Werner Lael, Aydemir Yusuf, Spronck Joey M A, Pode-Shakked Ben, van Hoesel Marliek, Shimshoni Elee, Polak-Charcon Sylvie, Talmi Liron, Eren Makbule, Weiss Batia, H J Houwen Roderick, Barshack Iris, Somech Raz, Nieuwenhuis Edward E S, Sagi Irit, Raas-Rothschild Annick, Middendorp Sabine, Shouval Dror S 1 Nov 2020, In: International journal of molecular sciences. 21 , p. 1-18 18 p.

Proteolytic Immuno-SRM Analysis of ATP7B in dried blood spots (DBS) for screening and diagnosis of Wilson Disease (WD)

Collins Christopher, Dayuha Remwilyn, Duong Phi, Horslen Simon P., Camarata Michelle, Coskun Ayse K., Houwen Roderick, Pop Tudor, Zoller Heinz, Weiss Karl Heinz, Schilsky Michael L., Ferenci Peter, Hahn Sihoun Nov 2020, In: Hepatology. 72 , p. 869A-870A

All research output

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