prof.dr. J.C. (Jan C.) Grutters

prof.dr. J.C. (Jan C.) Grutters

Full Professor
prof.dr. J.C. (Jan C.) Grutters
  • Department of Pulmonary Diseases

Research Programs

Infection & Immunity



Jan C. Grutters (1966) studied Medicine at the University of Nijmegen, and was trained in Respiratory Medicine at St. Antonius Hospital Nieuwegein and University Medical Center (UMC) Utrecht, the Netherlands. In 2001 he was awarded an ERS Research Fellowship at Imperial College and Royal Brompton Hospital London, resulting in his Thesis: ‘Genetic polymorphisms and phenotypes in sarcoidosis’. Since 2002 he works as a pulmonologist at St. Antonius Hospital, where he is head of the Interstitial Lung Diseases (ILD) Center of Excellence. He is also a member of the Lung Transplant Team at UMC Utrecht. From 2009 to 2011 he was head of training Pulmonology & Tuberculosis at St. Antonius Hospital. Additionally, he has been a Professor of ILD at University Utrecht since 2010, with his research focusing on genetics, biomarkers and novel therapies for progressive lung fibrosis, sarcoidosis, and various auto-immune, exposure-related and ultra-rare ILD. Throughout his career Prof. Grutters has supervised over 25 PhD students, authored and co-authored more than 300 scientific articles, and is regularly invited as speaker or chairman at international medical and scientific conferences. Lastly, he is a member of the editorial board of Sarcoidosis Vasculitis and Diffuse Lung Diseases, and vice president of the World Association of Sarcoidosis and Other Granulomatous Disorders.

Side Activities

vice president World Association of Sarcoidosis and Other Granulomatous Disorders (WASOG)
chairman Prof. Dr. Jaap Swierenga Stichting
member Sectie ILD (SIL) NVALT
member wetenschappelijke adviesraad (WAR) St Antonius  Onderzoeksfonds
member wetenschappelijke adviescommissie (WAC) Longfonds
member Horizonscan geneesmiddelen ZiN
member commissie dure geneesmiddelen NVALT
member medische adviesraad
member medische adviesraad Longfibrose patientenvereniging
member medische adviesraad Nationale Vereniging Sjogrenpatienten
medisch adviseur stichting LAM-Nederland
member Editorial Board of the journal SVDLD
member forum CPMS ERN-LUNG
member Nederlands asbestosis panel IAS 
member Adjudication Committee Pliant (Pliant)
member Steering Committee Sphinx trial (Actelion)


Research Output (320)

Outcomes in pulmonary sarcoidosis:results of a newly implemented prednisone protocol

Kampstra Nynke, Van der Wees Philip J, Van Beek Frouke T, Biesma Douwe H, Grutters Jan C, Van der Nat Paul B 28 Mar 2023, In: Sarcoidosis, Vasculitis, and Diffuse Lung Diseases. 40

Potential limitations of activity tracking devices in monitoring effects of treatment for sarcoidosis

Klein Rebecca, Judson Marc, Barkes Briana, Maier Lisa, Zeigler Joyce, Culver Daniel, Sweiss Nadera, Chen Edward, Hamzeh Nabeel, Grutters Jan, Valeyre Dominique, Singh Noopur, Spitzer Ginger, Shivas Tricha, Baughman Robert 28 Mar 2023, In: Sarcoidosis, Vasculitis, and Diffuse Lung Diseases. 40 , p. e2023010

Latent class analysis-based subgroups and response to corticosteroids in hospitalised community-acquired pneumonia patients:a validation study

Wittermans Esther, van der Zee Philip A, Qi Hongchao, Grutters Jan C, Voorn G Paul, Bos Willem Jan W, van de Garde Ewoudt M W, Endeman Henrik Mar 2023, In: ERJ Open Research. 9

Decreased Survival and Lung Function in Progressive Pulmonary Fibrosis

Platenburg Mark G J P, van der Vis Joanne J, Grutters Jan C, van Moorsel Coline H M 5 Feb 2023, In: Medicina (Kaunas, Lithuania). 59

MUC5B rs35705950 minor allele associates with older age and better survival in idiopathic pulmonary fibrosis

van der Vis Joanne J, Prasse Antje, Renzoni Elisabetta A, Stock Carmel J W, Caliskan Canay, Maher Toby M, Bonella Francesco, Borie Raphael, Crestani Bruno, Petrek Martin, Wuyts Wim A, Wind Anne E, Molyneaux Philip L, Grutters Jan C, van Moorsel Coline H M 26 Dec 2022, In: Respirology. 28 , p. 455-464 10 p.

European Respiratory Society Statement on Familial Pulmonary Fibrosis

Borie Raphael, Kannengiesser C, Antoniou Katerina, Bonella Francesco, Crestani Bruno, Fabre Aurélie, Froidure Antoine, Galvin Liam, Griese Matthias, Grutters Jan C, Molina-Molina Maria, Poletti Venerino, Prasse Antje, Renzoni Elisabetta, van der Smagt Jasper, van Moorsel Coline H M 22 Dec 2022, In: The European respiratory journal. 61

Association between anti-inflammatory effect of infliximab and small fiber neuropathy symptoms in patients with sarcoidosis

Raasing Lisette, Vogels Oscar J M, Veltkamp Marcel, Grutters Jan C 19 Dec 2022, In: Sarcoidosis, Vasculitis, and Diffuse Lung Diseases. 39

Potential interstitial lung abnormalities on chest X-rays prior to symptoms of idiopathic pulmonary fibrosis

Hoffman T. W., van Es H. W., Biesma D. H., Grutters J. C. Dec 2022, In: BMC Pulmonary Medicine. 22

Safety and tolerability of pirfenidone in asbestosis:a prospective multicenter study

Miedema Jelle R, Moor Catharina C, Veltkamp Marcel, Baart Sara, Lie Natascha S L, Grutters Jan C, Wijsenbeek Marlies S, Mostard Rémy L M Dec 2022, In: Respiratory research. 23 , p. 1-6

Characterization of the PF-ILD phenotype in patients with advanced pulmonary sarcoidosis

Schimmelpennink M C, Meek D B, Vorselaars A D M, Langezaal L C M, van Moorsel C H M, van der Vis J J, Veltkamp M, Grutters J C Dec 2022, In: Respiratory research. 23 , p. 1-10

All research output

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