prof. dr. ir. E.P.J.G. (Edwin) Cuppen
prof. dr. ir. E.P.J.G. (Edwin) Cuppen
- Group Cuppen, section Genetics
Biography
Biography
Edwin Cuppen is initiator and scientific director of the Hartwig Medical Foundation (part-time since 2015 and full time since 2021), a not-for-profit organisation that aims to improve cancer care by systematic whole genome sequencing analysis of tumors and that also maintains one of the world’s largest databases of cancer whole genome sequencing data enriched with clinical patient data. After his undergraduate and PhD training at Wageningen University and Radboud University Nijmegen as a molecular geneticist, he held research and group leader positions at the Netherlands Cancer Institute, the Hubrecht Institute and the UMC Utrecht. His expertise is in cancer genomics and functional genetics.
Side Activities
Academic advisory activities
Scientific Advisory Board InteRNA Technologies BV (miRNA-based therapeutics) (personal remuneration)
Advisory Board Clinical Whole Genome Sequencing Illumina (remuneration transfered to employer)
Employment at other organisation
Full time Scientific Director Hartwig Medical Foundation
Minimal appointment at UMC Utrecht
Fellowship and Awards
European Young Investigator Award 2005
NWO Vici grant 2013
Research Output (358)
de Witte Chris J, Kutzera Joachim, van Hoeck Arne, Nguyen Luan, Boere Ingrid A, Jalving Mathilde, Ottevanger Petronella B, van Schaik-van de Mheen Christa, Stevense Marion, Kloosterman Wigard P, Zweemer Ronald P, Cuppen Edwin, Witteveen Petronella O 2 Mar 2022, In: Cancers. 14 , p. 1-18
Nguyen Luan, Jager Myrthe, Lieshout Ruby, de Ruiter Petra E, Locati Mauro D, Besselink Nicolle, van der Roest Bastiaan, Janssen Roel, Boymans Sander, de Jonge Jeroen, IJzermans Jan N M, Doukas Michail, Verstegen Monique M A, van Boxtel Ruben, van der Laan Luc J W, Cuppen Edwin, Kuijk Ewart 18 Nov 2021, In: Communications biology. 4
van Riet Job, van de Werken Harmen J G, Cuppen Edwin, Eskens Ferry A L M, Tesselaar Margot, van Veenendaal Linde M, Klümpen Heinz-Josef, Dercksen Marcus W, Valk Gerlof D, Lolkema Martijn P, Sleijfer Stefan, Mostert Bianca 29 Jul 2021, In: Nature Communications. 12 , p. 1-14
Simons Martijn, van de Ven Michiel, Coupé Veerle, Joore Manuela, IJzerman Maarten, Koffijberg Erik, Frederix Geert, Uyl-De Groot Carin, Cuppen Edwin, van Harten Wim, Retèl Valesca 3 Jun 2021, In: Expert Review of Pharmacoeconomics and Outcomes Research. 21 , p. 343-351 9 p.
Cameron Daniel L, Jacobs Nina, Roepman Paul, Priestley Peter, Cuppen Edwin, Papenfuss Anthony T 11 May 2021, In: Bioinformatics (Oxford, England). 37 , p. 3115-3119
Roepman Paul, de Bruijn Ewart, van Lieshout Stef, Schoenmaker Lieke, Boelens Mirjam C., Dubbink Hendrikus J., Geurts-Giele Willemina R.R., Groenendijk Floris H., Huibers Manon M.H., Kranendonk Mariëtte E.G., Roemer Margaretha G.M., Samsom Kris G., Steehouwer Marloes, de Leng Wendy W.J., Hoischen Alexander, Ylstra Bauke, Monkhorst Kim, van der Hoeven Jacobus J.M., Cuppen Edwin 5 May 2021, In: Journal of Molecular Diagnostics. 23 , p. 816-833 18 p.
Ooft S. N., Weeber F., Schipper L., Dijkstra K. K., McLean C. M., Kaing S., van de Haar J., Prevoo W., van Werkhoven E., Snaebjornsson P., Hoes L. R., Chalabi M., van der Velden D., van Leerdam M., Boot H., Grootscholten C., Huitema A. D.R., Bloemendal H. J., Cuppen E., Voest E. E. 19 Apr 2021, In: ESMO open. 6 , p. 100103 1 p.
Mendelaar Pauline A J, Smid Marcel, van Riet Job, Angus Lindsay, Labots Mariette, Steeghs Neeltje, Hendriks Mathijs P, Cirkel Geert A, van Rooijen Johan M, Ten Tije Albert J, Lolkema Martijn P, Cuppen Edwin, Sleijfer Stefan, Martens John W M, Wilting Saskia M 25 Jan 2021, In: Nature Communications. 12 11 p.
Bollen Yannik, Stelloo Ellen, van Leenen Petra, van den Bos Myrna, Ponsioen Bas, Lu Bingxin, van Roosmalen Markus J., Bolhaqueiro Ana C.F., Kimberley Christopher, Mossner Maximilian, Cross William C.H., Besselink Nicolle J.M., van der Roest Bastiaan, Boymans Sander, Oost Koen C., de Vries Sippe G., Rehmann Holger, Cuppen Edwin, Lens Susanne M.A., Kops Geert J.P.L., Kloosterman Wigard P., Terstappen Leon W.M.M., Barnes Chris P., Sottoriva Andrea, Graham Trevor A., Snippert Hugo J.G. 2021, In: Nature Genetics. 53 , p. 1187-1195 9 p.
Verstegen Monique M A, Roos Floris J M, Burka Ksenia, Gehart Helmuth, Jager Myrthe, de Wolf Maaike, Bijvelds Marcel J C, de Jonge Hugo R, Ardisasmita Arif I, van Huizen Nick A, Roest Henk P, de Jonge Jeroen, Koch Michael, Pampaloni Francesco, Fuchs Sabine A, Schene Imre F, Luider Theo M, van der Doef Hubert P J, Bodewes Frank A J A, de Kleine Ruben H J, Spee Bart, Kremers Gert-Jan, Clevers Hans, IJzermans Jan N M, Cuppen Edwin, van der Laan Luc J W 14 Dec 2020, In: Scientific Reports. 10 , p. 1-16 16 p.