dr. M. Bartels

dr. M. Bartels

Assistant Professor - medical
dr. M. Bartels
  • Haematology patient care
  • Hematology/Van Creveldclinic

Research Programs

Child Health



Marije Bartels, MD, PhD is a pediatric hematologist working at the Pediatric Hematology department of the Wilhelmina Children’s Hospital/UMC Utrecht. She has a special interest in inherited bone marrow failure syndromes, and rare anemias. Following her PhD thesis in 2014, she continued her research on epigenomic regulation of myeloid disorders and on the biology of inherited bone marrow failure syndromes with a special focus on Diamond-Blackfan anemia and Severe Congenital Neutropenia.

Marije is an active member of national and international committees concerning bone marrow failure disorders in children (including PNH), and red blood cell pathology.

Side Activities

  • European Diamond Blackfan Consortium (EuroDBA) 

  • Scientific Working Group on Granulocytes and Constitutional Marrow Failure Disordres (European Hematology Association) 

  • Scientific Working Group on Red Cells and Iron Metabolism (European Hematology Association) 

  • Severe Chronic Neutropenia International Registry/Consortium

  • National working committee PNH (paroxsymal nocturnal hemoglobinuria)

  • National working committee bone marrow failure (within  “sectie kinderhematologie”)

  • Medical committee “Villa Pardoes” 

Fellowship and Awards

2013 Wilhelmina Children’s hospital Fund: Leading ladies research stimulation grant €125.000 euro

2012 American Society of Hematology (ASH) Abstract Achievement Award


Research Output (32)

Dried blood spot metabolomics reveals a metabolic fingerprint with diagnostic potential for Diamond Blackfan Anaemia

van Dooijeweert Birgit, Broeks Melissa H, van Beers Eduard J, Verhoeven-Duif Nanda M, van Solinge Wouter W, Nieuwenhuis Edward E S, Jans Judith J, van Wijk Richard, Bartels Marije 17 mei 2021, In: British Journal of Haematology. 193 , p. 1185-1193 9 p.

Ektacytometry Analysis of Post-splenectomy Red Blood Cell Properties Identifies Cell Membrane Stability Test as a Novel Biomarker of Membrane Health in Hereditary Spherocytosis

Berrevoets M C, Bos J, Huisjes R, Merkx T H, van Oirschot B A, van Solinge W W, Verweij J W, Lindeboom M Y A, van Beers E J, Bartels M, van Wijk R, Rab M A E 25 mrt 2021, In: Frontiers in Physiology. 12 , p. 1-10

Impact of the COVID-19 pandemic on quality of life and emotional wellbeing in patients with bone metastases treated with radiotherapy:a prospective cohort study

Bartels M M T J, Gal R, van der Velden J M, Verhoeff J J C, Verlaan J J, Verkooijen H M 25 feb 2021, In: Clinical & Experimental Metastasis. 38 , p. 209-217 9 p.

The interplay between drivers of erythropoiesis and iron homeostasis in rare hereditary anemias:Tipping the balance

Grootendorst Simon, de Wilde Jonathan, van Dooijeweert Birgit, van Vuren Annelies, van Solinge Wouter, Schutgens Roger, van Wijk Richard, Bartels Marije 2 feb 2021, In: International journal of molecular sciences. 22 17 p.

A Comprehensive Analysis of the Erythropoietin-erythroferrone-hepcidin Pathway in Hereditary Hemolytic Anemias

van Vuren Annelies J, Sharfo Alaa, Grootendorst Simon T, van Straaten Stephanie, Punt Arjen M, Petersen Jesper B, El Fassi Daniel, van Solinge Wouter W, Bartels Marije, van Wijk Richard, Glenthøj Andreas, van Beers Eduard J 2021, In: HemaSphere. 5 , p. e627

Oxygen gradient ektacytometry-derived biomarkers are associated with vaso-occlusive crises and correlate with treatment response in sickle cell disease

Rab Minke A E, Kanne Celeste K, Bos Jennifer, van Oirschot Brigitte A, Boisson Camille, Houwing Maite E, Gerritsma Jorn, Teske Erik, Renoux Celine, Riedl Jurgen, Schutgens Roger E G, Bartels Marije, Nur Erfan, Joly Philippe, Fort Romain, Cnossen Marjon H, van Wijk Richard, Connes Philippe, van Beers Eduard J, Sheehan Vivien A 11 nov 2020, In: American Journal of Hematology. 96 , p. E29-E32 4 p.

Untargeted metabolic profiling in dried blood spots identifies disease fingerprint for pyruvate kinase deficiency

Van Dooijeweert Birgit, Broeks Melissa H, Verhoeven-Duif Nanda M, Van Beers Eduard J, Nieuwenhuis Edward E S, Van Solinge Wouter W, Bartels Marije, Jans Judith J, Van Wijk Richard 10 sep 2020, In: Haematologica. Online ahead of print , p. 1-20

Rivaroxaban compared with standard anticoagulants for the treatment of acute venous thromboembolism in children: a randomised, controlled, phase 3 trial

Male Christoph, Lensing Anthonie W. A., Palumbo Joseph S., Kumar Riten, Nurmeev Ildar, Hege Kerry, Bonnet Damien, Connor Philip, Hooimeijer Helene L., Torres Marcela, Chan Anthony K. C., Kenet Gili, Holzhauer Susanne, Santamaria Amparo, Amedro Pascal, Chalmers Elizabeth, Simioni Paolo, Bhat Rukhmi V., Yee Donald L., Lvova Olga, Beyer-Westendorf Jan, Biss Tina T., Martinelli Ida, Saracco Paola, Peters Marjolein, Kallay Krisztian, Gauger Cynthia A., Massicotte M. Patricia, Young Guy, Pap Akos F., Majumder Madhurima, Smith William T., Heubach Jurgen F., Berkowitz Scott D., Thelen Kirstin, Kubitza Dagmar, Crowther Mark, Prins Martin H., Monagle Paul, , Bartels M jan 2020, In: Lancet haematology. 7 , p. E18-E27

Chapter 48: Erythrocyte Enzyme Disorders

Bartels M, van Beers Eduard, van Wijk Richard 2020, p. 749-784 35 p.

AML Subtype Is a Major Determinant of the Association between Prognostic Gene Expression Signatures and Their Clinical Significance

Wiggers Caroline R M, Baak Mirna L, Sonneveld Edwin, Nieuwenhuis Edward E S, Bartels Marije, Creyghton Menno P 10 sep 2019, In: Cell Reports. 28 , p. 2866-2877.e5

All research output

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