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prof. dr. I.E.C. (Iris) Sommer

Full Professor

  • Psychiatry

prof. dr. I.E.C. (Iris) Sommer

Research Programs

Biography

Iris Sommer obtained her PhD in 2004 cum laude on language lateralization in schizophrenia. After she finished her psychiatry residencies she worked as a psychiatrist in UMCU where she started the Voices Clinic. She started a research group investigating the pathophysiology of hallucinations and developed an interest in the treatment of schizophrenia.

She has several positions in editorial boards and committees:

  1. Elected member of the Young Academy of the Royal Dutch Academy of Arts and Science (DJA of KNAW)
  2. Invited member of AcademiaNet (500 leading women in science), headed by Angela Merckel
  3. Associate editor at Schizophrenia Bulletin (neuro-imaging section),
  4. Chair of the Dutch ZonMW program "Memorabel", part of the Deltaplan Dementie
  5. Member of the International Advisory Council SIRS (Schizophrenia International Research Society), 
  6. Member of the Steering Committee of the International Consortium on Hallucination Research
  7. Chair of the Scientific Committee of the Dutch Psychiatry Association 
  8. Member of the Dutch Committee for Research Integrity (Landelijk Orgaan Wetenschappelijke Integriteit)
  9. Member of the KNAW (Royal Dutch Academy of Arts and Sciences) Jury of the Heineken Medicine Price 
  10. Member of the KNAW (Royal Dutch Academy of Arts and Sciences) Committee KNAW-agenda large-scale research facilities (grootschalige onderzoeksfaciliteiten)

Research line

Pathophysiology and treatment of psychosis

Most recent key publications

1: Sommer IE, de Kort GA, Meijering AL, Dazzan P, Hulshoff Pol HE, Kahn RS, van Haren NE. How Frequent Are Radiological Abnormalities in Patients With Psychosis? A Review of 1379 MRI Scans. Schizophr Bull, 2012 Mar 13, Epub ahead of print
2: Sommer IE, de Witte L, Begemann M, Kahn RS. Nonsteroidal anti-inflammatory drugs in schizophrenia: ready for practice or a good start? A meta-analysis. J Clin Psychiatry, 2012 73(4):414-419.
3: Sommer IE, Slotema CW, Daskalakis J, Derks EM, Blom JD, van der Gaag M. The treatment of hallucinations in schizophrenia Schizophrenia Bulletin, 2012 Jun;38(4):704-14
4: Howes O, Shotbold PJ, Daalman K, Diederen KMJ, Kahn RS, Sommer IE. Dopaminergic function in the psychosis spectrum: an [18F]-DOPA imaging study in healthy individuals with auditory hallucinations. Schizophrenia Bulletin 2012 January 26
5: Sommer IE, Aleman A, Slotema CM, Schutter DJ. Transcranial stimulation for psychosis: the relationship between effect size and published findings. Am J Psychiatry, 2012 169(11):1211

Fellowship and Awards

  • 2005 Veni ZONMW € 200,000, nr. 916.56.172
    2008 Clinical Fellowship ZonMW €160,000, nr. 40-00703-97-270
    2009 Vidi, ZonMW €800,000, nr. 017.106.301 
    2012: Stanley foundation USA, $491,000 12T-008
    2012: Stanley foundation USA, $475,000, and 12T-009

Research Output (288)

Vasogenic edema versus neuroplasticity as neural correlates of hippocampal volume increase following electroconvulsive therapy

Nuninga Jasper O., Mandl René C.W., Froeling Martijn, Siero Jeroen C.W., Somers Metten, Boks Marco P., Nieuwdorp Wendy, Heringa Sophie, Sommer Iris E.C. 1 jul 2020, In: Brain Stimulation. 13 , p. 1080-1086 7 p.

The genetic architecture of the human cerebral cortex

Grasby Katrina L, Jahanshad Neda, Painter Jodie N, Colodro-Conde Lucía, Bralten Janita, Hibar Derrek P, Lind Penelope A, Pizzagalli Fabrizio, Ching Christopher R K, McMahon Mary Agnes B, Shatokhina Natalia, Zsembik Leo C P, Thomopoulos Sophia I, Zhu Alyssa H, Strike Lachlan T, Agartz Ingrid, Alhusaini Saud, Almeida Marcio A A, Alnæs Dag, Amlien Inge K, Andersson Micael, Ard Tyler, Armstrong Nicola J, Ashley-Koch Allison, Atkins Joshua R, Bernard Manon, Brouwer Rachel M, Buimer Elizabeth E L, Bülow Robin, Bürger Christian, Cannon Dara M, Chakravarty Mallar, Chen Qiang, Cheung Joshua W, Couvy-Duchesne Baptiste, Dale Anders M, Dalvie Shareefa, de Araujo Tânia K, de Zubicaray Greig I, de Zwarte Sonja M C, Klein Marieke, van Haren Neeltje E M, Veldink Jan H, Ayesa-Arriola Rosa, Cahn Wiepke, Hillegers Manon H J, Hulshoff Pol Hilleke E, Kahn René S, Ophoff Roel A, Sommer Iris E, 20 mrt 2020, In: Science. 367 , p. 1340-+

Hallucinations after Cardiac Surgery:A Prospective Observational Study

Ottens Thomas H, Sommer Iris E C, Begemann Marieke J, Schutte Maya, Cramer Maarten Jan, Suyker Willem J, Van Dijk Diederik, Slooter Arjen J C 2 mrt 2020, In: Medicina (Kaunas, Lithuania). 56 9 p.

To continue or not to continue?:Antipsychotic medication maintenance versus dose-reduction/discontinuation in first episode psychosis: HAMLETT, a pragmatic multicenter single-blind randomized controlled trial

Begemann Marieke J.H., Thompson Ilse A., Veling Wim, Gangadin Shiral S., Geraets Chris N.W., Van 'T Hag Erna, Müller-Kuperus Sanne J., Oomen Priscilla P., Voppel Alban E., Van Der Gaag Mark, Kikkert Martijn J., Van Os Jim, Smit H. Filip E., Knegtering Rikus H., Wiersma Sybren, Stouten Luyken H., Gijsman Harm J., Wunderink Lex, Staring Anton B.P., Veerman Selene R.T., Mahabir Amrita G.S., Kurkamp Jörg, Pijnenborg Gerdina H.M., Veen Natalie D., Marcelis Machteld, Grootens Koen P., Faber Gunnar, Van Beveren Nico J., Been Agaath, Van Den Brink Truus, Bak Maarten, Van Amelsvoort Therese A.M.J., Ruissen Andrea, Blanke Christine, Groen Karin, De Haan Lieuwe, Sommer Iris E.C. 7 feb 2020, In: Trials. 21

A characterization of the molecular phenotype and inflammatory response of schizophrenia patient-derived microglia-like cells

Ormel Paul R., Böttcher Chotima, Gigase Frederieke A.J., Missall Roy D., van Zuiden Welmoed, Fernández Zapata M. Camila, Ilhan Dilara, de Goeij Michelle, Udine Evan, Sommer Iris E.C., Priller Josef, Raj Towfique, Kahn René S., Hol Elly M., de Witte Lot D. 1 jan 2020, In: Brain, Behavior, and Immunity. 90 , p. 196-207 12 p.

Auditory hallucinations, top-down processing and language perception:a general population study

de Boer J. N., Linszen M. M.J., de Vries J., Schutte M. J.L., Begemann M. J.H., Heringa S. M., Bohlken M. M., Hugdahl K., Aleman A., Wijnen F. N.K., Sommer I. E.C. 1 dec 2019, In: Psychological medicine. 49 , p. 2772-2780 9 p.

Evolutionary modifications in human brain connectivity associated with schizophrenia

van den Heuvel Martijn P, Scholtens Lianne H, de Lange Siemon C, Pijnenburg Rory, Cahn Wiepke, van Haren Neeltje E M, Sommer Iris E, Bozzali Marco, Koch Kathrin, Boks Marco P, Repple Jonathan, Pievani Michela, Li Longchuan, Preuss Todd M, Rilling James K 14 nov 2019, In: Brain : a journal of neurology. 142 , p. 3991-4002 12 p.

Correction: Stratification and prediction of remission in first-episode psychosis patients: the OPTiMiSE cohort study (vol 9, 20, 2019):Stratification and prediction of remission in first-episode psychosis patients: the OPTiMiSE cohort study (Translational Psychiatry, (2019), 9, 1, (20), 10.1038/s41398-018-0366-5)

Martinuzzi Emanuela, Barbosa Susana, Daoudlarian Douglas, Ali Wafa Bel Haj, Gilet Cyprien, Fillatre Lionel, Khalfallah Olfa, Troudet Réjane, Jamain Stéphane, Fond Guillaume, Sommer Iris, Leucht Stefan, Dazzan Paola, McGuire Philip, Arango Celso, Diaz-Caneja Covadonga M., Fleischhacker Wolfgang, Rujescu Dan, Glenthøj Birte, Winter Inge, Kahn René Sylvain, Yolken Robert, Lewis Shon, Drake Richard, Davidovic Laetitia, Leboyer Marion, Glaichenhaus Nicolas, 21 jun 2019, In: Translational Psychiatry. 9 1 p.

MRI investigation of immune dysregulation in schizophrenia

Gangadin Shiral S, Nasib Lyliana G, Sommer Iris E C, Mandl René C W mei 2019, In: Current Opinion in Psychiatry. 32 , p. 164-169 6 p.

Volume increase in the dentate gyrus after electroconvulsive therapy in depressed patients as measured with 7T

Nuninga Jasper O, Mandl René C W, Boks Marco P, Bakker Steven, Somers Metten, Heringa Sophie M, Nieuwdorp Wendy, Hoogduin Hans, Kahn René S, Luijten Peter, Sommer Iris E C 12 mrt 2019, In: Molecular Psychiatry. 25 , p. 1559-1568 10 p.

All Research Output (288)