prof. dr. B.W. (Bas W.) Raaymakers

Full Professor

  • Experimental Clinical Physics Radiotherapy

prof. dr. B.W. (Bas W.) Raaymakers

Research Programs


Bas Raaymakers is working to improve cancer therapy by investigating, as well as developing, new high precision radiotherapy.
Together with prof Jan Lagendijk but also with industrial partners Elekta and Philips he designed and built a hybrid MRI accelerator to facilitate high precision, soft-tissue based image guidance for radiotherapy. This enables better radiotherapy via dose escalation while decreasing toxicity.
At the same time, the translation of this new technology to the clinic is pursued. For instance fast, on-line treatment planning, so that the patient is treated based on the latest state of the anatomy. This improves the current radiotherapy practice and at the same time is a requirement for smooth clinical introduction of the MRI accelerator.
Clinical work flow and procedures for different tumour sites are under investigation. Two major categories can be distinguished: The first is improving the existing radiotherapy patient treatments, so better conform the dose distribution to the tumour shape to minimise harm to the surroundings. The second is enabling radiotherapy as an alternative for surgery for patients currently not eligible for radiotherapy, e.g. highly mobile tumours in the kidney. The motion is too large to safely administer dose with conventional radiotherapy technology, with the on-line MRI guidance the motion uncertainty can be mitigated and radiation can be safely administered, offering a completely non-invasive treatment.

Side Activities

  • Member of International Advisory Committee of Physics in Medicine and Biology



Fellowship and Awards

  • VENI grant in 2003, Technical feasibility of the MRI accelerator

Research Output (172)

Deep learning prediction of proton and photon dose distributions for paediatric abdominal tumours

Guerreiro F, Seravalli E, Janssens G O, Maduro J H, Knopf A C, Langendijk J A, Raaymakers B W, Kontaxis C mrt 2021, In: Radiotherapy & Oncology. 156 , p. 36-42 7 p.

Impact of a vacuum cushion on intrafraction motion during online adaptive MR-guided SBRT for pelvic and para-aortic lymph node oligometastases

Werensteijn-Honingh Anita M, Jürgenliemk-Schulz Ina M, Gadellaa-Van Hooijdonk Christa G, Sikkes Gonda G, Vissers Nicole G P M, Winkel Dennis, Eppinga Wietse S C, Intven Martijn, Raaymakers Bas W, Kroon Petra S jan 2021, In: Radiotherapy & Oncology. 154 , p. 110-117 8 p.

Deep learning-enabled MRI-only photon and proton therapy treatment planning for paediatric abdominal tumours

Florkow Mateusz C, Guerreiro Filipa, Zijlstra Frank, Seravalli Enrica, Janssens Geert O, Maduro John H, Knopf Antje C, Castelein René M, van Stralen Marijn, Raaymakers Bas W, Seevinck Peter R 7 okt 2020, In: Radiotherapy & Oncology. 153 , p. 220-227 8 p.

Prostate intrafraction motion during the preparation and delivery of MR-guided radiotherapy sessions on a 1.5T MR-Linac

de Muinck Keizer D. M., Kerkmeijer L. G.W., Willigenburg T., van Lier A. L.H.M.W., Hartogh M. D.den, van der Voort van Zyp J. R.N., de Groot-van Breugel E. N., Raaymakers B. W., Lagendijk J. J.W., de Boer J. C.J. okt 2020, In: Radiotherapy and Oncology. 151 , p. 88-94 7 p.

Dosimetric feasibility of hypofractionation for SBRT treatment of lymph node oligometastases on the 1.5T MR-linac

Winkel D, Werensteijn-Honingh A M, Eppinga W S C, Intven M P W, Hes J, Snoeren L M W, Visser S A, Bol G H, Raaymakers B W, Jürgenliemk-Schulz I M, Kroon P S 16 sep 2020, In: Radiotherapy & Oncology. 154 , p. 243-248 6 p.

Anatomically-adaptive multi-modal image registration for image-guided external-beam radiotherapy

Zachiu Cornel, Denis de Senneville Baudouin, Willigenburg Thomas, van der Voort van Zyp Jochem R N, de Boer J C J, Raaymakers Bas W, Ries Mario G 7 aug 2020, In: Physics in medicine and biology. 65 , p. 215028

Delivered dose quantification in prostate radiotherapy using online 3D cine imaging and treatment log files on a combined 1.5T magnetic resonance imaging and linear accelerator system

Kontaxis Charis, de Muinck Keizer Daan M., Kerkmeijer Linda G.W., Willigenburg Thomas, den Hartogh Mariska D., van der Voort van Zyp Jochem R.N., de Groot-van Breugel Eline N., Hes Jochem, Raaymakers Bas W., Lagendijk Jan J.W., de Boer Hans C.J. jul 2020, In: Physics and Imaging in Radiation Oncology. 15 , p. 23-29 7 p.

Target coverage and dose criteria based evaluation of the first clinical 1.5T MR-linac SBRT treatments of lymph node oligometastases compared with conventional CBCT-linac treatment

Winkel Dennis, Bol Gijsbert H., Werensteijn-Honingh Anita M., Intven Martijn P.W., Eppinga Wietse S.C., Hes Jochem, Snoeren Louk M.W., Sikkes Gonda G., Gadellaa-van Hooijdonk Christa G.M., Raaymakers Bas W., Jürgenliemk-Schulz Ina M., Kroon Petra S. 1 mei 2020, In: Radiotherapy and Oncology. 146 , p. 118-125 8 p.

DeepDose:Towards a fast dose calculation engine for radiation therapy using deep learning

Kontaxis C, Bol G H, Lagendijk J J W, Raaymakers B W 7 apr 2020, In: Physics in medicine and biology. 65 10 p.

Dosimetric impact of soft-tissue based intrafraction motion from 3D cine-MR in prostate SBRT

de Muinck Keizer D M, Kontaxis C, Kerkmeijer L G W, van der Voort van Zyp J R N, van den Berg C A T, Raaymakers B W, Lagendijk J J W, de Boer J C J 17 jan 2020, In: Physics in Medicine and Biology. 65 , p. 25012 1 p.

All Research Output (172)