prof. dr. J.M. Beekman
Full Professor
- Pulmonology Research 2
- Onderzoek
Contact
Biography
Dr. J.M. Beekman obtained a PhD in molecular immunology in 2004, and performed multiple post docs in molecular and cell biology within various immunological settings. In October 2010, he became principle investigator at the UMC Utrecht, and started a novel translational research line focusing on developing novel therapeutic strategies for cystic fibrosis, a genetic disease characterized by aberrant ion and fluid homeostasis at mucosal surfaces leading to chronic infection and inflammation and early death around the 3rd to 4th decade of life.
‘People with chronic diseases living healthy lives: I strive to create breakthrough solutions for clinical needs of people with chronic diseases by scientific research that focuses on the development of novel diagnostic or therapeutic approaches. This requires a multidisciplinary approach in which basic and clinical research is aligned, and integrated with needs of patients, the private sector and regulatory authorities. Currently, I am particularly proud of leading a team that developed a highly innovative diagnostic assay that enables individualized therapy for people with cystic fibrosis that lead to direct clinical impact for people within 4 years after the initial discovery.’
Side Activities
Professional activities
2019- Vice-president organizing committee European CF society conference 2022
2016 – European CF society basic science working group – vice coordinator
2013 – Editorial board member of Rare Diseases
2013 – Editorial board member of PlosOne
2013 – Annual candidate selection committee for Eureka Institute of Translational Medicine
2010 – Reviewer for various journals including Cell, Nature Medicine, Nature Communications, PlosOne, Journal of Immunological Methods, Journal of Leukocyte Biology, Molecular Immunology, Journal of Medical Genetics, Journal of Cystic Fibrosis
Memberships
2019- UWE, collaboration Utrecht-Wageningen-Eindhoven
2019- Membership transition-team for animal-free innovation Utrecht
2014 – European Respiratory Society
2010 – European Cystic Fibrosis Society
2011 – Eureka Institute for Translational Medicine
2000 – Dutch Society of Immunology (NVVI
Research Output (90)
Berkers Gitte, van der Meer Renske, van Mourik Peter, Vonk Annelotte M, Kruisselbrink Evelien, Suen Sylvia Wf, Heijerman Harry Gm, Majoor Christof J, Koppelman Gerard H, Roukema Jolt, Janssens Hettie M, de Rijke Yolanda B, Kemper E Marleen, Beekman Jeffrey M, van der Ent Cornelis K, de Jonge Hugo R nov 2020, In: Journal of Cystic Fibrosis. 19 , p. 955-961 7 p.
Van Mourik Peter, van Haaren Paul, Kruisselbrink Evelien, Korkmaz Cemil, Janssens Hettie M., de Winter – de Groot Karin M., van der Ent Cornelis K., Hagemeijer Marne C., Beekman Jeffrey M. sep 2020, In: Journal of Cystic Fibrosis. 19 , p. 728-732 5 p.
Vonk Annelotte M, van Mourik Peter, Ramalho Anabela S, Silva Iris A L, Statia Marvin, Kruisselbrink Evelien, Suen Sylvia W F, Dekkers Johanna F, Vleggaar Frank P, Houwen Roderick H J, Mullenders Jasper, Boj Sylvia F, Vries Robert, Amaral Margarida D, de Boeck Kris, van der Ent Cornelis K, Beekman Jeffrey M 19 jun 2020, In: STAR protocols. 1 31 p.
de Poel E., Lefferts J. W., Beekman J. M. mrt 2020, In: Journal of Cystic Fibrosis. 19 Suppl 1 , p. S60-S64 5 p.
Amaral Margarida D., Beekman Jeffrey M. 1 jan 2020, In: Journal of Cystic Fibrosis. 19 , p. 11-15 5 p.
de Winter-de Groot Karin M, Berkers Gitte, Marck-van der Wilt Rozemarijn E P, van der Meer Renske, Vonk Annelotte, Dekkers Johanna F, Geerdink Margot, Michel Sabine, Kruisselbrink Evelien, Vries Rob, Clevers Hans, Vleggaar Frank P, Elias Sjoerd G, Heijerman Harry G M, van der Ent Cornelis K, Beekman Jeffrey M 14 nov 2019, In: Journal of Cystic Fibrosis. 19 , p. 614-619 6 p.
Chen Kevin G., Zhong Pingyu, Zheng Wei, Beekman Jeffrey M. 1 nov 2019, In: Drug Discovery Today. 24 , p. 2126-2138 13 p.
Mahon Clare S., Wildsmith Gemma C., Haksar Diksha, De Poel Eyleen, Beekman Jeffrey M., Pieters Roland J., Webb Michael E., Turnbull W. Bruce 30 okt 2019, In: Faraday discussions. 219 , p. 112-127 16 p.
Dekkers Johanna F., Alieva Maria, Wellens Lianne M., Ariese Hendrikus C.R., Jamieson Paul R., Vonk Annelotte M., Amatngalim Gimano D., Hu Huili, Oost Koen C., Snippert Hugo J.G., Beekman Jeffrey M., Wehrens Ellen J., Visvader Jane E., Clevers Hans, Rios Anne C. 1 jun 2019, In: Nature Protocols. 14 , p. 1756-1771 16 p.
Sun Xingshen, Yi Yaling, Yan Ziying, Rosen Bradley H., Liang Bo, Winter Michael C., Evans T. Idil Apak, Rotti Pavana G., Yang Yu, Gray Jaimie S., Park Soo Yeun, Zhou Weihong, Zhang Yulong, Moll Shashanna R., Woody Lisa, Tran Dao M., Jiang Licong, Vonk Annelotte M., Beekman Jeffrey M., Negulescu Paul, Van Goor Fred, Fiorino Dennis F., Gibson-Corley Katherine N., Engelhardt John F. 27 mrt 2019, In: Science Translational Medicine. 11